Evidence map›Paper›PMID 42290512›Full record

ArticleDialogues in clinical neuroscience2026

Poor sleep quality correlates with axial symptoms and mood problems in Parkinson's disease.

Seira Taniguchi, Yuta Kajiyama, Emi Shirahata, Yasuyoshi Kimura, Keita Kakuda, Lindun Ge, Kanako Asai, Yoichi Minami, Akifumi Kishi, Nicholas D'Cruz and 4 more

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Article in Dialogues in clinical neuroscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Seira TaniguchiDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID 0000-0002-5297-7716
Yuta KajiyamaDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID 0000-0001-7170-0758
Emi ShirahataDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yasuyoshi KimuraDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Keita KakudaDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Lindun GeDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Kanako AsaiDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.
Yoichi MinamiDepartment of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Akifumi KishiDepartment of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Nicholas D'CruzDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group (eNRGy), KU Leuven, Leuven, Belgium.
Hiroki R UedaDepartment of Systems Pharmacology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Moran GilatDepartment of Rehabilitation Sciences, Neurorehabilitation Research Group (eNRGy), KU Leuven, Leuven, Belgium.
Hideki MochizukiOsaka Toneyama Medical Center, Toyonaka, Japan.
Kensuke IkenakaDepartment of Neurology, The University of Osaka Graduate School of Medicine, Suita, Japan.ORCID 0000-0002-5559-1966

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSleep disturbances and impaired bed mobility are common in Parkinson's disease (PD). We examined whether objectively measured sleep efficiency is associated with axial motor impairment and explored its potential relationship with cognitive and mood profiles.

methodsTwenty-eight patients with PD underwent single-night EEG-based sleep monitoring and assessment of nocturnal turning. Partial correlations between sleep metrics and scores on motor, cognitive and mood outcomes were analysed, controlling for age, sex and the MDS-UPDRS 3. Family-wise error (FWE) correction was applied within each sleep predictor.

resultsPoor sleep efficiency correlated with higher MDS-UPDRS axial subscore (

conclusionPoor objective sleep quality was robustly associated with axial motor severity in PD, independent of overall motor burden. Sleep efficiency may represent a clinically accessible marker of shared brainstem-related pathology underlying axial dysfunction.

Indexed as

Mood DisordersParkinson DiseaseSleep QualitySleep Wake DisordersAgedElectroencephalographyFemaleHumansMaleMiddle AgedPolysomnographybed mobilitymood disturbancesParkinson’s diseasesleep

Identifiers

PMID42290512
PMCPMC13270875

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.