ArticleChemistry & biodiversity2026
Thymol Chemotype Thymus vulgaris L. Hydrolate: Volatile Chemical Fraction Composition and Antimicrobial Activity Against Bacterial and Fungal Pathogens.
Article in Chemistry & biodiversity, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The increasing prevalence of antimicrobial resistance necessitates the development of alternative antimicrobial agents derived from natural sources. This study evaluated the volatile chemical profile and antimicrobial activity of a thymol-containing hydrolate obtained from Thymus vulgaris L. against a panel of 14 clinically and economically relevant microorganisms. Headspace-gas chromatography-mass spectrometry analysis revealed thymol (79.9%) and linalool (17.4%) as the predominant constituents of the hydrolate. Antimicrobial activity was assessed using disc diffusion and broth microdilution assays to determine inhibition zones and minimum inhibitory concentrations. The hydrolate exhibited pronounced activity against Gram-positive bacteria, with the largest inhibition zones observed for Staphylococcus aureus and the lowest MIC values for the same strain (MIC
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