ArticleJournal of public health dentistry2026
Synergistic Effects of Social Determinants of Health and Periodontitis on Premature Cardiovascular Mortality: A Nationally Representative Cohort Study.
Article in Journal of public health dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeriodontitis, a prevalent chronic inflammatory disorder, is linked to an increased risk of cardiovascular disease (CVD). However, the impact of social determinants of health (SDoH) on premature CVD mortality in individuals with periodontitis remains poorly understood.
methodsData from 8277 US adults aged 30-74 years, collected from NHANES 2009-2014 with mortality follow-up through 2019, were analyzed. Periodontitis was defined according to CDC/AAP criteria, and premature CVD mortality was defined as death from CVD before age 75. A cumulative SDoH score was constructed based on eight indicators. Kaplan-Meier survival curves and log-rank tests compared survival probabilities across groups. Sensitivity analyses utilized Fine and Gray competing risk models.
resultsPeriodontitis was independently associated with an elevated risk of premature CVD mortality (HR = 2.21; 95% CI = 1.01-4.86), particularly among those with multiple adverse SDoH. A significant dose-response relationship was observed between cumulative SDoH burden and premature CVD mortality in the periodontitis cohort (P for trend = 0.03), but not in those without periodontitis. Food insecurity emerged as the sole individual SDoH independently linked to increased mortality risk. Kaplan-Meier curves revealed significantly lower cumulative survival among adults with periodontitis burdened with high SDoH (p < 0.01).
conclusionsPeriodontitis was associated with an increased risk of premature CVD mortality, especially in the presence of cumulative adverse SDoH, suggesting the need for integrated medical-dental care and broader strategies to address social inequities.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.