Evidence map›Paper›PMID 42289023›Full record

ArticleEJNMMI physics2026

Evaluation of modified window-based scatter compensation in quantitative

Irma Ceric Andelius, Anna Stenvall, Elias Nilsson, Erik Larsson, Johan Gustafsson

Abstract read
In one paragraph

Article in EJNMMI physics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Optimisation of Q.Clear (BSREM) Reconstruction Parameters forBioengineering (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Irma Ceric AndeliusRadiation Physics, Department of Haematology, Oncology, and Radiation Physics, Skåne University Hospital, Lund, Sweden. Irma.ceric_andelius@med.lu.se.ORCID http://orcid.org/0000-0001-8073-6277
Anna StenvallRadiation Physics, Department of Haematology, Oncology, and Radiation Physics, Skåne University Hospital, Lund, Sweden.ORCID http://orcid.org/0000-0002-7464-0030
Elias NilssonRadiation Physics, Department of Haematology, Oncology, and Radiation Physics, Skåne University Hospital, Lund, Sweden.
Erik LarssonRadiation Physics, Department of Haematology, Oncology, and Radiation Physics, Skåne University Hospital, Lund, Sweden.ORCID http://orcid.org/0009-0005-1137-4432
Johan GustafssonMedical Radiation Physics, Lund University, Lund, Sweden.ORCID http://orcid.org/0000-0002-1022-8370

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim was to evaluate bias and precision for

methodsListmode-data for a NEMA phantom and anthropomorphic phantom were reframed to accommodate the updated settings for MSC and MSC + P. Reconstruction was performed using OS-EM (two to 30 iterations, 10 subsets) with compensation for attenuation, scatter (DEW/TEW, MSC and MSC + P), spatial resolution, and penetration at 208 keV. Volumes-of-interest following the manufacturer-specified sphere sizes were defined and activity-concentration was quantified for each sphere and the total phantom activity across six (10 min) time-frames. Bias was evaluated with mean relative error and precision with coefficient of variation (CV).

resultsImaging at 208 keV generally results in similar activity concentrations and total activity estimates for MSC and MSC + P (mean relative error: - 24.8 to - 23.4%, CV: 0.6 and 0.7% for the larges sphere). For 113 keV, a slightly better precision is obtained for MSC and MSC + P (mean relative error: - 15.4 and - 21.5%, CV: 0.6 and 0.7% for the largest sphere in the NEMA phantom) but a larger bias compared with TEW (mean relative error - 7.1%, CV 0.8%). The major difference is for total activity where the MSC and MSC + P decrease bias compared to TEW (5 and 4% versus 21% for 113 keV in the NEMA phantom).

conclusionsThe improvement in activity-concentration accuracy in regard to bias and precision is modest in small-volume high activity-concentration regions. However, the findings suggest potential value in preservation of total activity for both MSC and MSC + P.

Indexed as

CZTLutetium-177Quantitative SPECTRing-configured SPECTScatter compensation

Identifiers

PMID42289023
PMCPMC13272698

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.