ArticleTrials2026
Glue versus Laser Ablation in Mini-invasive Pilonidal sinus surgery-the GLAMP study: a study protocol for a randomised controlled trial.
Article in Trials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06964763 (Laser Ablation Versus Fibrin Glue in Mini-invasive Pilonidal Sinus Disease Surgery), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Laser Ablation Versus Fibrin Glue in Mini-invasive Pilonidal Sinus Disease Surgery: a Prospective Randomized Controlled Trial
Who cites it
0 citing papers in PubMed.
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPilonidal sinus disease (PSD) is a chronic acquired condition leading to significant morbidity and healthcare costs in the working-age population. Randomised studies of PSD surgery are rare, and this applies especially to newer mini-invasive techniques. The purpose of our study is to compare two mini-invasive techniques in PSD surgery: laser ablation and fibrin glue treatment.
methodsThis randomised, prospective, multicentre superiority non-blinded study compares two parallel groups of PSD patients treated with laser ablation and fibrin glue. It compares the outcome of these mini-invasive treatment options in regards to both short-term outcome (healing rate) and long-term outcome (recurrence rate), and to the cost of these two treatment options. On the day of surgery, if the operating surgeon indicates that a patient is suitable for laser ablation and glue treatment, that patient is randomly assigned to one of those two surgery groups. After the operation, the operating surgeon completes the examination form. Patients are asked to complete a quality-of-life questionnaire (RAND-36/SF-36) preoperatively and 2 months after surgery. Further, at 2 months, patients also complete an additional questionnaire regarding any discomfort, symptoms, and recovery. All statistical analyses are performed by means of standard statistical software such as SPSS and NCSS. DISCUSSION: In PSD surgery, very few prospective randomised trials exist, which makes it difficult to compare various surgical methods. Earlier prospective randomised studies involving laser and glue include numbers of patients that are also relatively small, which is why comparisons of methods have not achieved statistical significance. Our study aims to compare two minimally invasive techniques to discover their short- and long-term differences regarding recovery and healing.
trial registrationThis trial was retrospectively registered in ClinicalTrials.gov on April 30, 2025 (NCT06964763). https://clinicaltrials.gov/study/NCT06964763?term=hermunen&rank=1 .
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