Evidence map›Paper›PMID 42288572›Full record

ArticleScientific reports2026

Sporulation generates stress-dependent phenotypic variability in the heterothallic industrial Saccharomyces cerevisiae Ethanol Red.

Viviana Paulon, Ameya Pankaj Gupte, Katarina Stojkov, Chiara Ruspi, Debora Casagrande Pierantoni, Marina Basaglia, Gianluigi Cardinali, Lorenzo Favaro, Laura Corte

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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Viviana PaulonWaste to Bioproducts-Lab, Department of Agronomy Food Natural Resources Animals and Environment (DAFNAE), Università di Padova, Viale dell'Università 16, Agripolis, Legnaro, 35020, PD, Italy.
Ameya Pankaj GupteWaste to Bioproducts-Lab, Department of Agronomy Food Natural Resources Animals and Environment (DAFNAE), Università di Padova, Viale dell'Università 16, Agripolis, Legnaro, 35020, PD, Italy.
Katarina StojkovDepartment of Pharmaceutical Sciences, University of Perugia, Borgo XX Giugno 74, Perugia, 06121, Italy.
Chiara RuspiDepartment of Pharmaceutical Sciences, University of Perugia, Borgo XX Giugno 74, Perugia, 06121, Italy.
Debora Casagrande PierantoniDepartment of Pharmaceutical Sciences, University of Perugia, Borgo XX Giugno 74, Perugia, 06121, Italy.
Marina BasagliaWaste to Bioproducts-Lab, Department of Agronomy Food Natural Resources Animals and Environment (DAFNAE), Università di Padova, Viale dell'Università 16, Agripolis, Legnaro, 35020, PD, Italy.
Gianluigi CardinaliDepartment of Pharmaceutical Sciences, University of Perugia, Borgo XX Giugno 74, Perugia, 06121, Italy.
Lorenzo FavaroWaste to Bioproducts-Lab, Department of Agronomy Food Natural Resources Animals and Environment (DAFNAE), Università di Padova, Viale dell'Università 16, Agripolis, Legnaro, 35020, PD, Italy. lorenzo.favaro@unipd.it.ORCID 0000-0002-5650-4422
Laura CorteDepartment of Pharmaceutical Sciences, University of Perugia, Borgo XX Giugno 74, Perugia, 06121, Italy.

Funding

Università degli Studi di Padova 2025DAFNAE1SIDPROGETTI-0001, 2025DAFNAE1DOR-00533
6 · The paper itself

Abstract

The industrial yeast Saccharomyces cerevisiae Ethanol Red is widely used in large-scale bioethanol production and is generally considered phenotypically stable because of its heterothallic diploid background. Here, we investigated whether extensive sporulation of this highly domesticated strain could generate functional diversification without genetic engineering. Thirty monosporal cultures (MSCs) were randomly selected and profiled for growth kinetics, CFU-based cultivability and Fourier-Transform Infrared (FTIR) fingerprints under three industrially relevant stressors, namely furfural (3 g L

Indexed as

EthanolSaccharomyces cerevisiaeSpores, FungalStress, PhysiologicalFermentationFormatesFuraldehydeIndustrial MicrobiologyPhenotypeSodium ChlorideSpectroscopy, Fourier Transform InfraredEthanolFormatesformic acidFuraldehydeSodium ChlorideBioethanolFormic acidFTIRFurfuralHeterothallismLignocellulosic inhibitorsNon-GMO strategiesSaccharomyces cerevisiaeSodium chlorideSporulationStress response

Identifiers

PMID42288572
PMCPMC13522619

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.