Evidence map›Paper›PMID 42288566›Full record

ArticleScientific reports2026

Multifunctional bioactivity of Portulaca oleracea seed oil: GC-MS-based characterization and in vitro evaluation.

Rushdy M Ahmed, Hafsa Nour El-Din Abd El-Kader Ebrahim, Mahmoud A Al-Saman, Mohamed Fawzy Ramadan, Rafaat M Elsanhoty

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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rushdy M AhmedSpecial Food And Nutrition Department, Agriculture Research Center, Food Technology Research Institute, Giza, Egypt.
Hafsa Nour El-Din Abd El-Kader EbrahimFood Technology Department, Faculty of Agriculture, Suez Canal University, Ismailia, Egypt.
Mahmoud A Al-SamanFaculty of Biotechnology, University of Sadat City, 22857/79, Sadat City, Egypt.
Mohamed Fawzy RamadanDepartment of Clinical Nutrition, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Kingdom of Saudi Arabia. mfhassanien@uqu.edu.sa.
Rafaat M ElsanhotyFaculty of Biotechnology, University of Sadat City, 22857/79, Sadat City, Egypt. rafaat.elsanhoty@gebri.usc.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purslane (Portulaca oleracea L.) is a widespread weed highly valued for its nutritional value, particularly its omega-3 fatty acid content. This study aimed to investigate the pharmacological properties and the phenolic and flavonoid contents of P. olecracea seed oil. P. oleracea seed oil was tested for antioxidant activity (DPPH· and ABTS), cell viability and cytotoxicity and anti-inflammatory activity. The contents of total phenolics, flavonoids, and constituents were characterized. The seed oil of P.oleracea had high flavonoid (4.53 mg/g) and phenolic (8.65 mg/g) content. The antioxidant activity of P. oleracea seed oil increased from 24.16% at a concentration of 0.5 µg/mL to 97.28% at a concentration of 1000 µg/mL. The MTT assay demonstrated that P. oleracea seed oil exhibited relatively weak to moderate cytotoxic activity against the A549, HepG-2, and MCF-7 cell lines. Lower concentrations of the seed oil extract exhibited anti-inflammatory activity, and these effects were compared with those of indomethacin as a positive control. GC-MS analysis showed that the seed oil of P. oleracea is rich in olean-12-ene-3,28-diol and 9-octadecenoic acid. It could be concluded that P. oleracea seed oil exhibits notable in vitro antioxidant and cytotoxic activities, which may be attributed to its content of flavonoids and phenolic compounds. However, further in vivo studies and toxicity evaluations are required to confirm its potential applications.

Indexed as

AntioxidantsPlant OilsPortulacaSeedsAnti-Inflammatory AgentsCell Line, TumorCell SurvivalFlavonoidsGas Chromatography-Mass SpectrometryHumansPhenolsAnti-Inflammatory AgentsAntioxidantsFlavonoidsPhenolsPlant OilsA549Anti-inflammatoryAntioxidantCell linesCytotoxicityFlavonoidsHepG-2MCF-7Phenolics

Identifiers

PMID42288566
PMCPMC13522612

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