Evidence map›Paper›PMID 42287602›Full record

ArticleProbiotics and antimicrobial proteins2026

Multi-Analytical Approach for the Quality and Functional Evaluation of Probiotic Formulations: The Case of Lactobacillus acidophilus LA-5

Margherita Bottaioli, Viola Termine, Aurora Botti, Beatrice Vitali, Diego Mora, Luca Laghi, Lorenzo Morelli, Loris Pinto, Alessia Marzulli, Federico Baruzzi and 1 more

Abstract read
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Article in Probiotics and antimicrobial proteins, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Margherita Bottaioli *Department for Sustainable Food Process (DiSTAS), Catholic University of the Sacred Heart, Via S. L. Bissolati 74, Cremona, 26100, Italy.
Viola Termine *Department of Food Environmental and Nutritional Sciences (DeFENS), University of Milan, Via G. Celoria 2, Via Mangiagalli 25, Milano, 20133, Italy.
Aurora BottiDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via P. Gobetti 87, Bologna, 40129, Italy.
Beatrice VitaliDepartment of Pharmacy and Biotechnology (FaBiT), University of Bologna, Via P. Gobetti 87, Bologna, 40129, Italy.
Diego MoraDepartment of Food Environmental and Nutritional Sciences (DeFENS), University of Milan, Via G. Celoria 2, Via Mangiagalli 25, Milano, 20133, Italy.
Luca LaghiDepartment of Agricultural and Food Sciences (DISTAL), University of Bologna, Piazza G. Goidanich 60, Cesena, 47521, Italy.
Lorenzo MorelliDepartment for Sustainable Food Process (DiSTAS), Catholic University of the Sacred Heart, Via S. L. Bissolati 74, Cremona, 26100, Italy.
Loris PintoInstitute of Sciences of Food Production, National Research Council of Italy (CNR-ISPA), Via G. Amendola 122/O, Bari, 70126, Italy.
Alessia MarzulliInstitute of Sciences of Food Production, National Research Council of Italy (CNR-ISPA), Via G. Amendola 122/O, Bari, 70126, Italy.
Federico BaruzziInstitute of Sciences of Food Production, National Research Council of Italy (CNR-ISPA), Via G. Amendola 122/O, Bari, 70126, Italy.
Alessandra FontanaDepartment for Sustainable Food Process (DiSTAS), Catholic University of the Sacred Heart, Via S. L. Bissolati 74, Cremona, 26100, Italy. alessandra.fontana@unicatt.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing use of probiotics in dietary supplements and functional foods highlights the need for robust analytical strategies to assess microbial viability, functional performance, and safety. Conventional culture-based methods may underestimate probiotic potential, particularly in multi-strain formulations. In this study, a multi-analytical framework was applied to evaluate four commercial formulations containing Lactobacillus acidophilus LA-5

Indexed as

Antimicrobial ActivityddPCRFlow CytometryGastrointestinal ResistanceMetabolomicsTaxonomic Identity

Identifiers

PMID42287602

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.