ArticleEuropean journal of applied physiology2026
Imbalanced cortisol/BDNF signals and oxidative stress underscore temporary cognitive impairment in deep divers after in water/surface decompression: proof of concept.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Systemic Oxy-Inflammatory, Hormonal, and Mood Responses to a Ski Mountaineering Competition: Preliminary Evidence from Military Athletes.Sports (Basel, Switzerland) · 2026Article
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8 authors.
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Abstract
backgroundMilitary deep divers experience extreme environmental stressors, particularly with prolonged diving. Alterations such as hyperbaric conditions and variable O
methodsThree Deep Divers (Italian Navy-Comsubin), with an average age of 31.00 ± 2.64 years, carried out a technical surface-supplied bounce diving in open water (-89m) in the Mediterranean Sea. From them, we collected saliva and urine samples before diving (T0), after deep diving followed by water-surface decompression (T1), and after complete subemersion (T2). To assess for pro-inflammatory and stress conditions, we evaluated reactive oxygen species (ROS) production, DNA oxidation (8-OHdG), total antioxidant capacity (TAC), nitric oxide (NO
resultsAt T1, ROS production increased (+ 121%) and continued to increase just to T2, coupled to a continuous rise in 8-OHdG, and a contemporary decline in TAC. Simultaneously, cortisol levels increased while those of dopamine decreased (-27%). BDNF levels were also sizably elevated (+ 175%). Conversely, no changes in pro-inflammatory markers and NO concentrations were evident.
conclusionsOxidative stress and neurotransmitter increase and/or decrease (according to biomarkers evaluated) occur post-deep diving, suggesting preventative strategies to mitigate cognitive impairment.
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