Evidence map›Paper›PMID 42287376›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Cervical curvature changes and neurological outcomes following non-fusion surgery for cervical space-occupying lesions in adults: a multicenter retrospective study.

Qixuan Jiang, Qiangwei Wang, Zhaowen Gu, Yucheng Ren, Deqing Peng, Xin Huang, Aiqin Chen, Jingyin Chen, Chi Gu, Guangyu Ying and 1 more

Abstract readMulticenter Study
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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Qixuan Jiang *Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Qiangwei Wang *Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. wangqiangwei@zju.edu.cn.
Zhaowen Gu *Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yucheng Ren *Department of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Deqing PengDepartment of Neurosurgery, Zhejiang Provincial Peoples Hospital, Hangzhou, China.
Xin HuangDepartment of Neurosurgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Aiqin ChenDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jingyin ChenDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Chi GuDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Guangyu YingDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yongjian ZhuDepartment of Neurosurgery, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. neurosurgery@zju.edu.cn.

Funding

Key Research and Development Program of Zhejiang Province 2024C03071National Natural Science Foundation of China 82471390National Natural Science Foundation of China 82504165
6 · The paper itself

Abstract

purposeKyphosis is a potential complication after resection of cervical space-occupying lesions, and whether non-fusion surgery can maintain cervical stability remains controversial. We aimed to investigate long-term changes in neurological function and cervical curvature after non-fusion surgery in adults, and to further explore the prognostic factors.

methodsWe reviewed adult patients who underwent non-fusion surgery for resection of cervical space-occupying lesions at three neurosurgical centers. The neurological function grade defined by modified McCormick scale, the change of cervical Cobb lordotic angle (CLA), and the incidence of progressive kyphotic deformity and secondary fusion surgery were described. We also conducted regression analyses to explore the factors influencing CLA and neurological function.

resultsA total of 211 adults were enrolled in our study. The long-term follow-up showed that 84% patients achieved good neurological outcomes. The average change of CLA was 1.2 ± 7.2 degrees. There was no significant difference in CLA at follow-up compared with the preoperative value. Progressive kyphotic deformity was observed in 9(7%) patients and none of the patients underwent secondary spinal fixation surgery. Regression analysis identified LAMP surgery as a protective factor for CLA change (β = 5.519[1.994, 9.043]) while C-2 involvement as a risk factor (β=-3.433[-6.250, -0.616]).

conclusionsThe majority of patients undergoing non-fusion surgery for cervical space-occupying lesions achieve favorable neurological function and maintain ideal cervical curvature. Those patients whose C-2 were involved require more frequent follow-up.

Indexed as

Cervical VertebraeKyphosisPostoperative ComplicationsAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSpinal FusionTreatment OutcomeCervical curvature changeCervical space-occupying lesionsNeurological functionNon-fusionProgressive kyphotic deformity

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.