Evidence map›Paper›PMID 42287350›Full record

ArticleEating and weight disorders : EWD2026

Internalized weight stigma and obesity-related quality of life in adults with obesity or overweight: a cross-sectional study across clinical and community settings.

Gian Mauro Manzoni, Elena Tomba, Valentina Gardini, Hellas Cena, Romana Schumann, Donatella Ballardini, Lorenzo Maria Donini, Emilia Manzato, Giovanni Gravina, Daniele Di Pauli and 2 more

Abstract read
In one paragraph

Article in Eating and weight disorders : EWD, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Gian Mauro ManzoniPsychology Research Laboratory, Ospedale San Giuseppe, IRCCS Istituto Auxologico Italiano, Verbania, Italy. gm.manzoni@auxologico.it.
Elena TombaDepartment of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.
Valentina GardiniDepartment of Psychology "Renzo Canestrari", University of Bologna, Bologna, Italy.
Hellas CenaDepartment of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy.
Romana SchumannCentro Gruber, Eating Disorders Outpatient Clinic, Bologna, Italy.
Donatella BallardiniCentro Gruber, Eating Disorders Outpatient Clinic, Bologna, Italy.
Lorenzo Maria DoniniDepartment of Experimental Medicine, Sapienza University, Rome, Italy.
Emilia ManzatoPrivate Hospital "Salus", Eating and Weight Disorders Centre, Ferrara, Italy.
Giovanni GravinaCentro Disturbi Alimentari e Obesità, Casa di Cura San Rossore, Pisa, Italy.
Daniele Di PauliPrivate Psychotherapist, Verona, Italy.
Gianluca CastelnuovoPsychology Research Laboratory, Ospedale San Giuseppe, IRCCS Istituto Auxologico Italiano, Verbania, Italy.
Chiara MazzoniCentro Gruber, Eating Disorders Outpatient Clinic, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeInternalized weight stigma (IWS) is a known correlate of reduced quality of life (QoL) in individuals with obesity or overweight. However, few studies have examined whether this association differs across different recruitment settings. This study aimed to assess the association between IWS and obesity-related QoL in adults with obesity or overweight recruited from clinical settings or from the community, while adjusting for established psychological and demographic predictors.

methodsA total of 313 individuals with obesity were recruited from six obesity treatment centers, and 139 with obesity (n = 72) or overweight (n = 67) were recruited from the community via online survey. Participants completed self-report measures of IWS (Weight Bias Internalization Scale), obesity-related QoL (Laval Questionnaire), depressive symptoms (BDI-II), binge eating (BES), and attitudes toward people with obesity (ATOP). Multiple regression models tested the effect of IWS across QoL domains, with interaction terms by recruitment setting and adjustment for covariates.

resultsFirst exploratory analyses revealed some significant differences across clinical centers in both predictors and QoL domains, which warranted the adjustment of the alpha level to 0.005 for all subsequent regression models. IWS significantly predicted poorer QoL in emotional, social, and sexual domains across all groups, including individuals with overweight from the community. It was also associated with lower hygiene-related QoL, but only among individuals with obesity from clinical centers. No direct effect of IWS was found on physical functioning or symptom burden. Depressive symptoms and BMI were strong covariates in most regression models.

conclusionsIWS is independently associated with psychological and interpersonal aspects of QoL across clinical and community settings. These findings underscore the importance of addressing internalized weight stigma in both therapeutic interventions and public health efforts. LEVEL OF EVIDENCE: Level III: Evidence obtained from well-designed cohort or case-control analytic studies.

Indexed as

ObesityOverweightQuality of LifeSelf ConceptSocial StigmaAdultCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedSurveys and QuestionnairesInternalized weight stigmaObesity-related Quality of LifeObesity stigmaWeight stigma

Identifiers

PMID42287350
PMCPMC13279737

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.