Evidence map›Paper›PMID 42287290›Full record

ArticleJACC. Case reports2026

Marked Troponin Elevation Mimicking Acute Coronary Syndrome After Pulsed-Field Ablation for Atrial Fibrillation.

Tharindra S Pathiranage, Swatam Jain, Sharnvir S Chattha, Dhiraj Narula

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tharindra S PathiranageDepartment of Internal Medicine, Sunrise Health GME Consortium, Las Vegas, Nevada, USA. Electronic address: Tharindrapathirana93@gmail.com.
Swatam JainDepartment of Internal Medicine, Sunrise Health GME Consortium, Las Vegas, Nevada, USA.
Sharnvir S ChatthaDepartment of Internal Medicine, Sunrise Health GME Consortium, Las Vegas, Nevada, USA.
Dhiraj NarulaDepartment of Internal Medicine, Sunrise Health GME Consortium, Las Vegas, Nevada, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulsed-field ablation (PFA) is an emerging nonthermal modality for atrial fibrillation. Although troponin elevation is common after ablation, markedly elevated levels mimicking acute coronary syndrome (ACS) are uncommon. CASE PRESENTATION: A 77-year-old woman presented with acute chest pain within 24 hours after undergoing PFA for atrial fibrillation. High-sensitivity troponin I was markedly elevated at 12,221 ng/L. Electrocardiography showed no ischemic changes, and imaging revealed no obstructive coronary artery disease. Serial troponin levels demonstrated a steady decline. DISCUSSION: Marked troponin elevation may occur after PFA and can mimic ACS. Clinical interpretation should integrate symptoms, electrocardiographic findings, imaging, and biomarker trends rather than relying solely on troponin magnitude. TAKE-HOME MESSAGE: Markedly elevated troponin levels after PFA may exceed commonly reported ranges and mimic ACS; however, diagnosis should rely on clinical context, electrocardiographic findings, imaging, and biomarker trends rather than on troponin magnitude alone.

Indexed as

acute coronary syndrome mimicatrial fibrillationcardiac biomarkersmyocardial injurypulsed-field ablationtroponin elevation

Identifiers

PMID42287290
PMCPMC13554862

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.