Evidence map›Paper›PMID 42287286›Full record

ArticleBiomacromolecules2026

Reversing the Fold: Polyanionic Macrocycle Dissolves αA66-80 Crystallin Peptide Aggregates.

Frank Boateng Osei, Yuvraj Dangat, Roi Yasay, Josephine Esposto, Kwaku Twum, Robert J Huber, Sanela Martic, Hedieh Torabifard, Ngong Kodiah Beyeh

Abstract read
In one paragraph

Article in Biomacromolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Frank Boateng OseiDepartment of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.
Yuvraj DangatDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080-3021, United States.
Roi YasayDepartment of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.
Josephine EspostoDepartment of Biology, Environmental and Life Sciences Program, Trent University, 1154 Peterborough, Ontario K9L 0G2, Canada.ORCID 0000-0001-9012-3044
Kwaku TwumDepartment of Pathology and Laboratory Medicine, Boston University School of Medicine, Boston, Massachusetts 02118, United States.
Robert J HuberDepartment of Biology, Environmental and Life Sciences Program, Trent University, 1154 Peterborough, Ontario K9L 0G2, Canada.
Sanela MarticDepartment of Biology, Environmental and Life Sciences Program, Trent University, 1154 Peterborough, Ontario K9L 0G2, Canada.ORCID 0000-0001-6642-2298
Hedieh TorabifardDepartment of Chemistry and Biochemistry, The University of Texas at Dallas, 800 West Campbell Road, Richardson, Texas 75080-3021, United States.ORCID 0000-0003-0687-6858
Ngong Kodiah BeyehDepartment of Chemistry, Oakland University, 146 Library Drive, Rochester, Michigan 48309-4479, United States.ORCID 0000-0003-3935-1812

Funding

Computational framework to investigate the inorganic ion transportersR35GM155106 · NIGMS · UNIVERSITY OF TEXAS DALLAS · PI Hedieh Torabifard · 2024 to 2026
$1.2M
Toward Targeting GPR31 and GPR39 Signaling in Diabetic RetinopathyR21EY036537 · NEI · OAKLAND UNIVERSITY · PI AL-SHABRAWEY, MOHAMED AL-SAYED · 2024 to 2025
$375k
NEI NIH HHS R21 EY036537NIGMS NIH HHS R35 GM155106
6 · The paper itself

Abstract

Cataract is a leading cause of blindness worldwide, with no clear pharmacological agent for treatment. An octa-sulfonated polyanionic resorcinarene

Indexed as

CrystallinsMacrocyclic CompoundsPeptide FragmentsPeptidesPhenylalanineProtein AggregatesCalixarenesCalorimetryPolyelectrolytesCalixarenesCrystallinsMacrocyclic CompoundsPeptide FragmentsPeptidesPhenylalaninePolyelectrolytesProtein Aggregatesresorcinarene

Identifiers

PMID42287286
PMCPMC13327089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.