Evidence map›Paper›PMID 42287047›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2026

[Association analysis between genetic nurturing effects of

Jingxian Wu, Liuyan Zheng, Huan Yu, Huairong Wang, Shuting Xie, Yalin Chen, Teng Li, Mengying Wang, Xueying Qin, Tao Wu and 3 more

Abstract readEnglish Abstract
PubMed Full text at PMC
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jingxian WuDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Liuyan ZhengDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Huan YuDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Huairong WangDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Shuting XieDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Yalin ChenDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Teng LiDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Mengying WangKey Laboratory of Epidemiology of Major Disease (Peking University), Ministry of Education, Beijing 100191, China.
Xueying QinDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Tao WuDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Dafang ChenDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Yiqun WuDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.
Yonghua HuDepartment of Epidemiology and Biostatistics, Peking University School of Public Health, Beijing 100191, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the genetic nurture effect of parental genotypes on the risk of ischemic stroke (IS) in offspring and to elucidate the parental origin-specific differences in this effect.

methodsThis study utilized data from the "Family Cohort of Common Chronic Non-communicable Diseases in Rural Areas of Northern China". A total of 530 core families and sibling pairs were selected, comprising 1 005 offspring. Single nucleotide polymorphisms (SNPs) within the

resultsA total of 1 005 offspring from 530 families were included, comprising 308 IS patients (30.6%) with a mean age of 56.3 years. Sixteen independent SNPs associated with IS genetic nurture effects were identified (9 in

conclusionThis study provides evidence that multiple IS susceptibility loci within the

Indexed as

alpha CateninGenetic Predisposition to DiseaseIschemic StrokePolymorphism, Single NucleotideStrokeAgedChinaFemaleGenotypeHumansMaleMiddle Agedalpha CateninCTNNA1 protein, humanCTNNA gene familyGene-environment interactionsGenetic nurture effectIschemic strokeParent-of-origin specific

Identifiers

PMID42287047
PMCPMC13268844

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.