Evidence map›Paper›PMID 42287016›Full record

ArticleLiver international : official journal of the International Association for the Study of the Liver2026

Impact of Breath Holding on Spleen Stiffness Measured by 100 Hz Vibration Controlled Transient Elastography.

Sebastiana Atzori, Pierluigi Meloni, Marco Arru, Gianpaolo Vidili

Abstract read
In one paragraph

Article in Liver international : official journal of the International Association for the Study of the Liver, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Impact of Breath Holding on Spleen Stiffness Measured by 100 Hz Vibration Controlled Transient Elastography.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sebastiana AtzoriDepartment of Internal Medicine, Azienda Ospedaliero Universitaria di Sassari, Sassari, Italy.
Pierluigi MeloniDepartment of Internal Medicine, Azienda Ospedaliero Universitaria di Sassari, Sassari, Italy.
Marco ArruDepartment of Medicine, Surgery and Pharmacy, University of Sassari, Sassari, Italy.ORCID 0000-0002-7112-5025
Gianpaolo VidiliDepartment of Internal Medicine, Azienda Ospedaliero Universitaria di Sassari, Sassari, Italy.ORCID 0000-0002-8903-5829

Funding

Fondazione di Sardegna FDS2019VIDILI
6 · The paper itself

Abstract

BACKGROUNDS AND

aimsUltrasound-based spleen stiffness measurement (SSM) is a valid non-invasive tool to assess portal hypertension (PH) in chronic liver disease. Whereas the role of the respiratory phase during liver stiffness measurements is established, no study has specifically addressed how respiration influences SSM by transient elastography.

aimsTo evaluate the influence of respiration on SSM assessed with FibroScan 630 (Echosens, Paris, France).

methodsEighty-three patients with chronic liver disease of different aetiologies underwent SSM using vibration-controlled transient elastography (VCTE).

resultsSSM acquired during a normal respiratory cycle showed better diagnostic accuracy than measurements obtained during breath-hold after deep inspiration (AUROC 0.835 [95% CI 0.743-0.928] vs. 0.798 [95% CI 0.697-0.899]).

conclusionSSM by VCTE should be performed during quiet breathing, as it showed good diagnostic accuracy for predicting the presence of oesophageal varices (OV) in patients with chronic liver disease.

Indexed as

Breath HoldingElasticity Imaging TechniquesEsophageal and Gastric VaricesHypertension, PortalLiver DiseasesSpleenAdultAgedChronic DiseaseFemaleHumansMaleMiddle AgedVibrationnon‐invasive ultrasound methodsportal hypertensionspleen stiffnesstransient elastography

Identifiers

PMID42287016
PMCPMC13263714

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.