ArticleThe American journal of case reports2026
A 44-Year-Old Male Manual Laborer With Nonunion of a Femoral Neck Fracture Treated With Ultrasound-Guided Percutaneous Injections of Platelet-Rich Plasma: A Case Report.
Article in The American journal of case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
BACKGROUND Femoral neck fractures are prone to nonunion due to compromised vascular supply. While surgical revision remains the standard of care, biological approaches such as platelet-rich plasma (PRP), a concentrate rich in growth factors that enhance bone healing, offer a less invasive option. This report describes the case of a 44-year-old man, who worked as a manual laborer, with a femoral neck fracture nonunion who refused further surgery and was treated with ultrasound-guided percutaneous injections of PRP. CASE REPORT Nine months after undergoing internal fixation for a complex hip fracture, a 44-year-old man presented with persistent right hip pain and gait impairment. Radiographic evaluation confirmed the diagnosis of an oligotrophic nonunion of the femoral neck. The patient declined surgical revision, and a nonsurgical biological intervention was pursued. This consisted of 3 ultrasound-guided percutaneous injections of autologous PRP administered at 1- to 2-week intervals, followed by a structured, phased rehabilitation protocol. Over the ensuing 7 months, serial radiographic follow-up demonstrated progressive bony union. The treatment resulted in complete resolution of pain at rest, minimal pain on weight-bearing, and a successful return to unassisted walking and light work. No adverse events were reported. CONCLUSIONS This case demonstrates that a series of ultrasound-guided percutaneous PRP injections can serve as a successful, minimally invasive, non‑surgical alternative for promoting union in selected cases of femoral neck nonunion, potentially allowing patients to avoid revision surgery.
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