ArticlePharmacology research & perspectives2026
Natural Monoterpene Stylosin Induced Anticancer Effects on Human Colon Carcinoma Cells.
Article in Pharmacology research & perspectives, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Colorectal carcinoma (CRC) ranks among the top five most common malignancies globally, characterized by a high incidence and poor prognosis. Hepatocyte growth factor receptor (HGFR), a tyrosine kinase oncoprotein, plays a critical role in tumor progression. This study aimed to investigate the effects of stylosin (STL), a natural monoterpene, on human CRC cells, with focus on its potential interactions with HGFR. For computational analysis, the expression of HGFR was assessed in CRC tissues, pharmacokinetics of STL were predicted, and the interaction between STL and HGFR was determined by molecular docking. For experimental studies, STL was isolated from Ferula ovina roots via thin layer chromatography, and its structure was confirmed by
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