ArticleJournal of cardiothoracic surgery2026
Coronary thrombosis after Bentall's procedure in a patient with Ehlers-Danlos syndrome: a case report.
Article in Journal of cardiothoracic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundAcute coronary syndrome (ACS) following cardiac valve replacement is a rare but severe complication. Patients with vascular Ehlers-Danlos syndrome (vEDS) may exhibit an increased propensity for coronary thrombosis due to their genetic predisposition. After Bentall surgery, coronary manipulation and early postoperative anticoagulation instability may further contribute to thrombotic risk, particularly after mechanical valve implantation. CASE PRESENTATION: A 33-year-old male presenting with acute chest pain underwent a Bentall procedure for vEDS-complicated type A aortic dissection and received postoperative anticoagulation. Twenty days postoperatively, angiography and IVUS revealed a thrombus at the left anterior descending artery (LAD) ostium. Following a multidisciplinary discussion, percutaneous coronary intervention (PCI) was successfully performed to remove the thrombus and restore blood flow.
conclusionsWe discuss the risk of ACS following cardiac surgery, especially in vEDS patients, as well as strategies for early identification, timely intervention, and optimization of perioperative anticoagulation management.
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