Evidence map›Paper›PMID 42286558›Full record

Trial reportInternational breastfeeding journal2026

Breastfeeding and complementary feeding practices in Madagascar: results of a secondary analysis of the freeBily trial.

Valentina Marchese, André Brito, Raphäel Rakotozandrindrainy, Norbert Georg Schwarz, Njary Rakotozandrindrainy, Tahinamandranto Rasamoelina, Mala Rakoto Andrianarivelo, Jeannine Solonirina, Elveric Fesia Ratiaharison, Mickael Radomanana and 11 more

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in International breastfeeding journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Valentina MarcheseResearch Group: Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
André BritoResearch Group: Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Raphäel RakotozandrindrainyUniversity of Antananarivo, Antananarivo, Madagascar.
Norbert Georg SchwarzDepartment of Infectious Diseases Epidemiology, Bernhard Nocht Institute for Tropical Medicine (BNITM), Hamburg, Germany.
Njary RakotozandrindrainyUniversity of Antananarivo, Antananarivo, Madagascar.
Tahinamandranto RasamoelinaCentre d'Infectiolologie Charles Mérieux (CICM), Antananarivo, Madagascar.
Mala Rakoto AndrianariveloCentre d'Infectiolologie Charles Mérieux (CICM), Antananarivo, Madagascar.
Jeannine SolonirinaUniversity of Antananarivo, Antananarivo, Madagascar.
Elveric Fesia RatiaharisonInfectious Diseases Service, University Hospital Tambohobe, Fianarantsoa, Madagascar.
Mickael RadomananaUniversity of Antananarivo, Antananarivo, Madagascar.
Tiana RandrianarisoaInfectious Diseases Service, University Hospital Tambohobe, Fianarantsoa, Madagascar.
Philipp KleinResearch Group: Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Jule HameisterResearch Group: Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Leonard GungaResearch Group: Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.
Irina KislayaGerman Center for Infection Research (DZIF), Hamburg-Borstel-Lübeck-Riems, Hamburg, Germany.
Anna JaegerGerman Center for Infection Research (DZIF), Hamburg-Borstel-Lübeck-Riems, Hamburg, Germany.
Govert van DamLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Jürgen MayGerman Center for Infection Research (DZIF), Hamburg-Borstel-Lübeck-Riems, Hamburg, Germany.
Rivo Andry RakotoariveloInfectious Diseases Service, University Hospital Tambohobe, Fianarantsoa, Madagascar.
Daniela FuscoResearch Group: Implementation Research, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany. fusco@bnitm.de.
freeBILy consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breastfeeding and complementary feeding are key public health practices for child development and attainment of optimal nutritional status, with additional beneficial effects on maternal health. In Madagascar, we conducted a secondary analysis of a cluster randomised clinical trial data (Pan-African Clinical Trial Register PACTR201905784271304) to assess the practice of delayed complementary feeding (DCF) at nine months postpartum (T3 visit) and continued breastfeeding (CB) at 24 months (T4). Factors associated with the prevalence of DCF were investigated using a generalized estimating equation (GEE) for binomial outcome with logarithmic link function to account for clustering, prevalence ratio (PR) with 95% confidence intervals (CIs) were estimated. A Cox proportional hazards model was used to assess factors associated with breastfeeding termination (BT). A total of 1863 women were evaluated at T3, 2332 at T4. At T3, 1848 (98.8%) were breastfeeding and 479 (25.7%) were delaying complementary feeding. At T4, 1269 (54.4%) were breastfeeding. Median time for BT was 21 months (range 2-25). Secondary education (PR = 0.67, CI 0.49-0.93) and anaemia (PR = 0.75, CI 0.65-0.88) were associated with lower prevalence of DCF at T3, being a farmer with a higher prevalence (PR = 3.45, CI 1.90-6.28). Older age was associated with longer CB (hazard ratio 0.68, CI 0.49-0.96 for 30-50 years). The association between being farmer mothers and DCF at nine months requires further investigations. Two main lines of public health actions are identified: health education, with intergenerational mentoring initiatives from older to younger women, and integrating maternal and child health programmes to improve both maternal anaemia and child development in a life-cycle approach.

Indexed as

Breast FeedingInfant Nutritional Physiological PhenomenaAdultFemaleHumansInfantInfant, NewbornMadagascarMothersProportional Hazards ModelsSecondary Data AnalysisYoung AdultBreastfeedingChild healthComplementary feedingMadagascarMaternal healthNutritional global targetsResource-limited countries

Identifiers

PMID42286558
PMCPMC13270689

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.