Evidence map›Paper›PMID 42286489›Full record

ArticleBMC medical research methodology2026

Application of Q-methodology in chronic disease research: a scoping review.

Li Zhang, Xue Yang, Guirong Li

Abstract readScoping Review
In one paragraph

Article in BMC medical research methodology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Li Zhang *School of Nursing, Chengdu Medical College, Chengdu, 610500, China.
Xue Yang *School of Nursing, Chengdu Medical College, Chengdu, 610500, China.
Guirong LiSchool of Nursing, Chengdu Medical College, Chengdu, 610500, China. 384895848@qq.com.

Funding

Chengdu Medical College YCX2025-01-126Research Project of Psychological and Behavioral Science Research Center of Deyang Key Research Base for Philosophy and Social Sciences XLYXW2026012
6 · The paper itself

Abstract

backgroundAs the global population ages, the burden of chronic disease management continues to intensify. Guided by a patient-centered medical philosophy, there is an urgent need to develop research methods capable of capturing in depth the complex subjective experiences of patients, caregivers, and healthcare providers. This approach aims to address the limitations of current homogeneous intervention strategies. Q-methodology, a research method for exploring the complexities of human subjectivity, demonstrates significant potential across multiple fields, including the management of chronic diseases. This study aims to examine the characteristics of existing Q-methodology research on chronic diseases, including research questions, methodological variations, and implications for research in this field.

methodsThis study followed the updated scope review methodology of the Joanna Briggs Institute, as well as the PRISMA-ScR guidelines (Preferred Reporting Items for Systematic Reviews and Scoping Reviews). Literature searches were conducted from inception to November 1, 2025, across four databases: PubMed, Web of Science Core Collection, Embase, and Cochrane Library. The search was limited to English-language publications. Data extraction primarily utilized the Q-methodology evaluation and review tool.

resultsFifteen studies from six countries were included. Participants were individuals with chronic diseases, caregivers, and healthcare providers. Sample sizes ranged from 23 to 60 in the Q Sample and 13 to 136 in the P Sample. Research questions fell into three areas: identifying needs and preferences for support and interventions (N = 9), comparing differences in viewpoints (N = 4), and understanding patients' intrinsic cognition and experiences (N = 2). Each study reported 3 to 8 unique perspectives. Q-methodology use is increasing in chronic disease research; however, methodological variations persist. Notable differences appear in determining the Q sample, selecting P-samples, conducting Q-sorting, and data analysis. Its application in chronic disease studies facilitates the exploration of group perspectives and the comparative analysis of differences in viewpoints, enabling a deeper capture of complex subjective experiences within populations.

conclusionsPreliminary evidence suggests that Q-methodology has clinical utility and scientific rigor in chronic disease research. However, given the limited number of studies and methodological heterogeneity, more research is needed to confirm these findings. Future efforts should focus on developing more scientifically comprehensive reporting checklists to standardize their use.

trial registrationAs the research did not directly involve animals or humans, no ethical review was conducted.

Indexed as

Biomedical ResearchResearch DesignChronic DiseaseHumansChronic DiseasesMixed methodsQ-MethodologyScoping Review

Identifiers

PMID42286489
PMCPMC13374176

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.