Evidence map›Paper›PMID 42286351›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Accelerated sagittal remodeling of lumbar facet joints following L4-L5 posterior lumbar interbody fusion: a longitudinal MRI study.

Xiang Liu, Wei-Cong Zhang, Pei-Jie Liang, Xiao-Jun Lu, Li-Hsing Chou, Yu-Han Wang, Zhi-Hai Su, Lian-Jun Yang, Hai Lu

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Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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5 · Who and what money

Authors and funding

9 authors.

Xiang LiuDepartment of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Wei-Cong ZhangJiangmen Key Laboratory of Artificial Intelligence in Medical Image Computation and Application, Jiangmen Central Hospital, Jiangmen, China.
Pei-Jie LiangDepartment of Spine Surgery, Foshan Fosun Chancheng Hospital, Foshan, China.
Xiao-Jun LuDepartment of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Li-Hsing ChouDepartment of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Yu-Han WangDepartment of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China.
Zhi-Hai SuDepartment of Spine Surgery, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China. 851567029@qq.com.
Lian-Jun YangDepartment of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China. drlianjunyang@163.com.
Hai LuDepartment of Spine Surgery, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, China. lvhai@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to investigate whether the progression of lumbar facet joint angle (FJA) in adjacent segment degeneration (ASD) occurs more rapidly in the sagittal plane compared to a matched control group.

methodsThis retrospective longitudinal study included 35 individuals from three hospitals who underwent L4-L5 posterior lumbar interbody fusion (PLIF) surgery and had preoperative lumbar magnetic resonance imaging (MRI) scans. These patients also underwent follow-up MRI scans approximately four to five years postoperatively. A control group, matched for age and gender, was included for comparative analysis. MRI data were assessed using grading scales for facet joint degeneration (FJD) and lumbar intervertebral disc degeneration (IDD). FJA measurements were derived from T2-weighted axial images.

resultsNo significant progression of IDD was found in either group. Within the PLIF group, a more rapid progression of FJD was observed at the bilateral L5-S1 and right L3-L4 segments in comparison to the control group (P < 0.05). In contrast, the control group exhibited consistent lumbar FJA across all segments. Postoperative MRI scans of the PLIF group, however, demonstrated a significant reduction in FJA on both sides of the L3-L4 segment and on the left side of the L5-S1 segment (P < 0.05), with no significant changes observed at the L2-L3 segment and the right side of the L5-S1 segment. A significant negative correlation was found between the change in FJA (ΔFJA) and the change in FJD (ΔFJD) at the left L5-S1 segment in the PLIF group (ρ = -0.335, P = 0.049).

conclusionAccelerated sagittal facet remodeling occurs at segments adjacent to L4-L5 PLIF and correlates with facet degeneration. These hypothesis-generating preliminary findings suggest that FJA measurement has the potential to serve as an imaging biomarker for ASD risk, though this interpretation remains to be validated in larger prospective cohorts. The findings underscore the need for long-term postoperative surveillance.

Indexed as

Adjacent segment degenerationFacet joint angleFacet joint degenerationLumbar intervertebral disc degenerationPosterior lumbar interbody fusionRadiography analysisSagittalization

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.