Evidence map›Paper›PMID 42286244›Full record

ArticleNature microbiology2026

Bacterial cell division protein FtsZ complexes with a phage protein to activate bacterial immunity.

Tong Zhang, Anastasiia Nadieina, Carl B W Soderstrom, Julia E Ramseyer, Christina R Beck, Kyo Coppieters 't Wallant, Chloé Martens, Abel Garcia-Pino, Michael T Laub

Abstract read
In one paragraph

Article in Nature microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tong ZhangDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-4745-8580
Anastasiia NadieinaCellular and Molecular Microbiology, Faculté des Sciences, Université libre de Bruxelles, Brussels, Belgium.ORCID http://orcid.org/0009-0001-5801-0768
Carl B W SoderstromDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Julia E RamseyerDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.ORCID http://orcid.org/0000-0003-4001-9980
Christina R BeckDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Kyo Coppieters 't WallantBiochemistry and Structural Biology, Université libre de Bruxelles, Brussels, Belgium.ORCID http://orcid.org/0000-0003-2358-999X
Chloé MartensBiochemistry and Structural Biology, Université libre de Bruxelles, Brussels, Belgium.
Abel Garcia-PinoCellular and Molecular Microbiology, Faculté des Sciences, Université libre de Bruxelles, Brussels, Belgium. abel.garcia.pino@ulb.be.ORCID http://orcid.org/0000-0002-0634-0300
Michael T LaubDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. laub@mit.edu.ORCID http://orcid.org/0000-0002-8288-7607

Funding

EC | EU Framework Programme for Research and Innovation H2020 | H2020 Priority Excellent Science | H2020 European Research Council (H2020 Excellent Science - European Research Council) CoG DiStRes, n° 864311Fonds De La Recherche Scientifique - FNRS (Belgian National Fund for Scientific Research) CDR J.0065.23F and J.0085.25; EQP U.N029.25; PDR T.0090.22; POC CDR R.E004.25; WELBIO ADV X.1520.24FFonds De La Recherche Scientifique - FNRS (Belgian National Fund for Scientific Research) F.45322.22
6 · The paper itself

Abstract

Many antiphage defence systems directly bind a specific phage-encoded protein that acts similar to a pathogen-associated molecular pattern to activate an immune response. Such activation is often assumed to occur independent of host factors. Here we demonstrate that the antiphage defence protein CapRel

Indexed as

Bacterial ProteinsCytoskeletal ProteinsViral ProteinsBacteriophagesCell DivisionModels, MolecularProtein BindingBacterial ProteinsCytoskeletal ProteinsFtsZ protein, BacteriaViral Proteins

Identifiers

PMID42286244
PMCPMC13423816

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.