Evidence map›Paper›PMID 42286152›Full record

ArticleScientific reports2026

Early cell-wall stress signatures enable 20-min ATR-FTIR discrimination of MRSA and MSSA.

Wilbur Hudson, Michael Nelson, Caroline C Taylor, Alexander Marchesani, Diyali Sil, Chayan Dutta, Eric S Gilbert, Gary Hastings, Yi Jiang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wilbur HudsonDepartment of Mathematics and Statistics, Georgia State University, Atlanta, 30303, USA.
Michael Nelson *Department of Physics and Astronomy, Georgia State University, Atlanta, 30303, USA.
Caroline C Taylor *Department of Biology, Georgia State University, Atlanta, 30303, USA.
Alexander Marchesani *Department of Biology, Georgia State University, Atlanta, 30303, USA.
Diyali SilDepartment of Chemistry, Georgia State University, Atlanta, 30303, USA.
Chayan DuttaDepartment of Chemistry, Georgia State University, Atlanta, 30303, USA.
Eric S GilbertDepartment of Biology, Georgia State University, Atlanta, 30303, USA.
Gary HastingsDepartment of Physics and Astronomy, Georgia State University, Atlanta, 30303, USA.
Yi JiangDepartment of Mathematics and Statistics, Georgia State University, Atlanta, 30303, USA. yjiang12@gsu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid identification of methicillin-resistant Staphylococcus aureus (MRSA) is crucial for early optimization of antibiotic treatment, but current routine susceptibility testing typically requires 48-72 h. Attenuated total reflectance Fourier-transform infrared (ATR-FTIR) spectroscopy has emerged as a promising approach for bacterial identification and has recently been used to distinguish MRSA from methicillin-sensitive S. aureus (MSSA) after 60-120 min of β-lactam exposure. Here, we test whether ATR-FTIR can resolve MRSA versus MSSA within the first hour of antibiotic challenge. We exposed three MSSA (ATCC 6538, WKZ1, RN4220) and four MRSA (ATCC 43300, USA300-JE2, WKZ2, CA629) strains to sub-MIC ampicillin (0.5 μg/mL) and acquired spectra from 800 to 1800 cm

Indexed as

Cell WallMethicillin-Resistant Staphylococcus aureusStaphylococcus aureusAmpicillinAnti-Bacterial AgentsMicrobial Sensitivity TestsSpectroscopy, Fourier Transform InfraredAmpicillinAnti-Bacterial Agents

Identifiers

PMID42286152
PMCPMC13518314

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.