Evidence map›Paper›PMID 42286005›Full record

ArticleScientific reports2026

Luminescent heparin-functionalized carbon dots with potential applications in nanoparticle-protein interactions and cell imaging.

Ipsita Kumar Sen, Maidul Hossain, Debesh Chandra Bhattacharya, Anoop Kumar, Ahmet Kati, Amiya Kumar Panda, M Deniz Yilmaz, Amit Kumar Mandal

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ipsita Kumar SenDepartment of Chemistry, Government General Degree College Salboni, Paschim Medinipur-721516, Salboni, West Bengal, India. senipsitakumar007@gmail.com.
Maidul HossainDepartment of Chemistry, Vidyasagar University, Midnapore, 721102, West Bengal, India.
Debesh Chandra BhattacharyaDepartment of Microbiology, Vidyasagar University, Midnapore, 721102, West Bengal, India.
Anoop KumarDepartment of Biotechnology, University of North Bengal, Darjeeling, 734013, India.
Ahmet KatiDepartment of Biotechnology, Institute of Health Sciences, University of Health Sciences Türkiye, Istanbul, 34668, Türkiye.
Amiya Kumar PandaDepartment of Chemistry, Vidyasagar University, Midnapore, 721102, West Bengal, India.
M Deniz YilmazDepartment of Basic Sciences, Faculty of Engineering, Necmettin Erbakan University, Konya, 42140, Türkiye. deniz.yilmaz@erbakan.edu.tr.
Amit Kumar MandalChemical Biology Laboratory, Department of Sericulture, Raiganj University, North Dinajpur-733134, Raiganj, West Bengal, India. amitmandal08@gmail.com.

Funding

DST-SERB India EEQ/2021/000058
6 · The paper itself

Abstract

In this study, we report the synthesis and comprehensive characterization of heparin-capped carbon dots (Hep-C-dots) prepared using D-glucose as a carbon precursor and heparin, a negatively charged polysaccharide belonging to the glycosaminoglycan family, as a capping and stabilizing agent. The obtained Hep-C-dots exhibited a uniform nanoscale size distribution with an average diameter of 2.5 ± 0.5 nm and a high negative surface charge (- 36.8 mV). Full characterization of as-synthesized Hep-C-dots has been done by several state-of-the-art analytical techniques, such as transmission electron microscopy (TEM), X-ray diffraction (XRD), UV-visible spectroscopy, Fourier-transform infrared (FTIR) spectroscopy, and zeta potential analysis. The interactions between Hep-C-dots and key human proteins, namely human methemoglobin (HB) and human serum albumin (HSA), were investigated via fluorescence spectroscopy, demonstrating significant binding affinities with K

Indexed as

CarbonCarbon Quantum DotsHeparinNanoparticlesA549 CellsAnimalsCell SurvivalHumansProtein BindingSpectroscopy, Fourier Transform InfraredX-Ray DiffractionCarbonHeparincarbon dotscytotoxicity assayhemocompatibilityHeparinluminescentnanomaterialsprotein–nanoparticle interaction

Identifiers

PMID42286005
PMCPMC13519020

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.