Evidence map›Paper›PMID 42285941›Full record

ArticleNature communications2026

Late-stage generation of

Anika Schick, Marc San Jose Gracia, Hans Christian D Hammershøj, Johan Broddefalk, Pablo Martínez-Pardo, Vitus J Enemærke, Lena von Sydow, Anna Holub, Ranganath Gopalakrishnan, Kim S Mühlfenzl and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Anika SchickEarly Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden. anika.schick@astrazeneca.com.ORCID 0009-0003-4200-7390
Marc San Jose GraciaSanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, Frankfurt am Main, Germany.
Hans Christian D HammershøjInterdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Aarhus, Denmark.
Johan BroddefalkMedicinal Chemistry, CVRM, Discovery Sciences, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.ORCID 0009-0002-3971-4652
Pablo Martínez-PardoEarly Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden.ORCID 0000-0003-4819-0854
Vitus J EnemærkeInterdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Aarhus, Denmark.ORCID 0000-0002-3099-2544
Lena von SydowMedicinal Chemistry, R&I, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Anna HolubSanofi-Aventis Deutschland GmbH, R&D, Integrated Drug Discovery, Industriepark Höchst, Frankfurt am Main, Germany.
Ranganath GopalakrishnanMedicinal Chemistry, CVRM, Discovery Sciences, Biopharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.
Kim S MühlfenzlEarly Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Gothenburg, Sweden.ORCID 0000-0003-3700-0891
Troels SkrydstrupInterdisciplinary Nanoscience Center (iNANO) and Department of Chemistry, Aarhus University, Aarhus, Denmark.ORCID 0000-0001-8090-5050
Charles S ElmoreEarly Chemical Development, Pharmaceutical Sciences, R&D, AstraZeneca, Boston, MA, USA. chad.elmore@astrazeneca.com.ORCID 0000-0001-7434-8307

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptides constitute a well-established and rapidly expanding field in the contemporary pharmaceutical drug landscape. Studies with

Indexed as

Carbon RadioisotopesLysinePeptidesTritiumIsotope LabelingSemaglutideCarbon RadioisotopesLysinePeptidesSemaglutideTritium

Identifiers

PMID42285941
PMCPMC13272800

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.