Evidence map›Paper›PMID 42285940›Full record

Trial reportSignal transduction and targeted therapy2026

Liposomal doxorubicin plus nab-paclitaxel with/without chemoradiotherapy in head and neck adenoid cystic carcinoma: single-arm phase II study.

Xinxin Zhang, Jian Wei, Nanxiang Chen, Kun Liu, Robert Liang, Lin Ma, Zhigang Song, Xiang Gu, Xiaohong Chen, Shiming Yang

Abstract readClinical Trial, Phase IIMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Signal transduction and targeted therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xinxin ZhangDepartment of Otolaryngology, College of Otolaryngology Head and Neck Surgery, The 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China. xinxinzhang66@hotmail.com.
Jian WeiDepartment of Otolaryngology, College of Otolaryngology Head and Neck Surgery, The 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.
Nanxiang ChenDepartment of Otolaryngology, College of Otolaryngology Head and Neck Surgery, The 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.
Kun LiuDepartment of Otolaryngology, College of Otolaryngology Head and Neck Surgery, The 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.
Robert LiangPeking University Health Science Center, Beijing, China.
Lin MaDepartment of Radiation Oncology, Chinese PLA General Hospital, Beijing, China.
Zhigang SongDepartment of Pathology, The First Medical Center, Chinese PLA General Hospital, Beijing, China.
Xiang GuDepartment of Otolaryngology, College of Otolaryngology Head and Neck Surgery, The 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China. summygu@126.com.
Xiaohong ChenDepartment of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China. trchxh@163.com.
Shiming YangDepartment of Otolaryngology, College of Otolaryngology Head and Neck Surgery, The 6th Medical Center of Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China. yangsm301@263.net.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given no standard therapies, this single-arm, open-label, multicenter phase II study was conducted in unresectable locally advanced or recurrent/metastatic adenoid cystic carcinoma of the head and neck (LA or R/M ACCHN). Patients received chemotherapeutic nanomedicines (20 mg/m

Indexed as

Antineoplastic Combined Chemotherapy ProtocolsCarcinoma, Adenoid CysticChemoradiotherapyDoxorubicinHead and Neck NeoplasmsPaclitaxelAdultAgedAlbuminsFemaleHumansMaleMiddle AgedPolyethylene Glycols130-nm albumin-bound paclitaxelAlbuminsDoxorubicinliposomal doxorubicinPaclitaxelPolyethylene Glycols

Identifiers

PMID42285940
PMCPMC13263355

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.