Evidence map›Paper›PMID 42285538›Full record

ArticleEnvironmental science & technology2026

Hypophosphite Is a Naturally Occurring Selective Inhibitor of Syntrophic Methanogenesis.

Ruiwen Hu, Matt E Weaver, Leslie A Day, John Mark Marquez, Heidi S Aronson, David A O Meier, Pedro Romero, Mohd Farid Abdul Halim, Alesha D Maxwell, Kyle C Costa and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental science & technology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Ruiwen HuEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.ORCID 0009-0007-1039-6490
Matt E WeaverEnergy and Biosciences Institute, University of California Berkeley, Berkeley, California 94720, United States.
Leslie A DayDepartment of Microbiology and Immunology, Geisel School of Medicine at Dartmouth College, Dartmouth, New Hampshire 03755, United States.
John Mark MarquezInternational Rice Research Institute, Los Baños 4031, Philippines.ORCID 0009-0002-2719-3343
Heidi S AronsonEnergy and Biosciences Institute, University of California Berkeley, Berkeley, California 94720, United States.
David A O MeierEnergy and Biosciences Institute, University of California Berkeley, Berkeley, California 94720, United States.
Pedro RomeroDepartment of Animal Science, University of California, Davis, Davis, California 95616, United States.
Mohd Farid Abdul HalimDepartment of Plant and Microbial Biology, University of Minnesota, St. Paul, Minnesota 55108, United States.
Alesha D MaxwellPrairie View A&M University, Prairie View, Texas 77446, United States.
Kyle C CostaDepartment of Plant and Microbial Biology, University of Minnesota, St. Paul, Minnesota 55108, United States.
Adam M DeutschbauerEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Morgan N PriceEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Matthias HessDepartment of Animal Science, University of California, Davis, Davis, California 95616, United States.
Koushik Singha RoyShell India Markets Pvt. Ltd., Bangalore 562149, India.
Ando Mariot RadanielsonInternational Rice Research Institute, Los Baños 4031, Philippines.
John D CoatesEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.
Nicolas TsesmetzisShell International Exploration and Production Inc, Shell Technology Centre, Houston, Texas 77082, United States.ORCID 0000-0001-5246-0568
Hans K CarlsonEnvironmental Genomics and Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States.ORCID 0000-0002-1583-5313

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbial methanogenesis is a major contributor to global warming, and methane fluxes represent a loss of energy and electrons from industrial ecosystems. The chemical space of methane control strategies is still underexplored. Most known methanogenesis inhibitors target methanogenic archaeal enzymes. However, interference with the exchange of syntrophic electron carriers (H

Indexed as

MethanePhosphatesAnimalsCattleDiphosphatesFermentationMethanococcusOryzaRumenDiphosphatesdiphosphoric acidMethanePhosphateschemical inhibitorgreenhouse gasmethanereduced phosphorusriceruminantsyntrophy

Identifiers

PMID42285538
PMCPMC13374091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.