Evidence map›Paper›PMID 42284480›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2026

Polymer-Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring.

Xiaolin Li, Hongqiang Li, Ming Han, Xin Liu, Mingjun Ding, Ziying Niu, Dongyang Liu, Liyuan Yang, Lizhen Zhang, Francisco Hernández-Ramírez and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Xiaolin LiTianjin Key Laboratory of Optoelectronic Detection Technology and Systems, School of Electronics and Information Engineering, Tiangong University, Tianjin, China.
Hongqiang LiTianjin Key Laboratory of Optoelectronic Detection Technology and Systems, School of Electronics and Information Engineering, Tiangong University, Tianjin, China.ORCID https://orcid.org/0000-0003-2870-6171
Ming HanEngineering Teaching Practice Training Center, Tiangong University, Tianjin, China.
Xin LiuSchool of Chemical Engineering and Technology, Tiangong University, Tianjin, China.
Mingjun DingTianjin Key Laboratory of Optoelectronic Detection Technology and Systems, School of Electronics and Information Engineering, Tiangong University, Tianjin, China.
Ziying NiuTianjin Key Laboratory of Optoelectronic Detection Technology and Systems, School of Electronics and Information Engineering, Tiangong University, Tianjin, China.
Dongyang LiuTianjin Key Laboratory of Intelligent Control of Electrical Equipment, School of Control Science and Engineering, Tiangong University, Tianjin, China.
Liyuan YangTianjin Key Laboratory of Optoelectronic Detection Technology and Systems, School of Electronics and Information Engineering, Tiangong University, Tianjin, China.
Lizhen ZhangTianjin Key Laboratory of Optoelectronic Detection Technology and Systems, School of Electronics and Information Engineering, Tiangong University, Tianjin, China.
Francisco Hernández-RamírezDepartment of Electronics and Biomedical Engineering, Universitat de Barcelona, Barcelona, Spain.
Lu CaoChest Hospital, Tianjin University, Tianjin, China.
Enbang LiCenter for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia.

Funding

Key Project of Natural Science Foundation of Tianjin 25JCZDJC00290Key Research and Development Program of Tianjin 25YFGKHZ00090Key Research and Development Program of Tianjin 25YFXTHZ00580National Natural Science Foundation of China 61675154Open Project of Tianjin Key Laboratory of Optoelectronic Detection Technology and System 2025LODTS102Open Project of Tianjin Key Laboratory of Optoelectronic Detection Technology and System 2025LODTS109Open Project of Tianjin Key Laboratory of Optoelectronic Detection Technology and System 2025LODTS201
6 · The paper itself

Abstract

Optical sensors are essential in medical diagnostics and detect variations in light intensity, phase, wavelength, polarization, or interference. However, conventional devices face limitations in multiplexing capability, surface functionalization, and integration. Here, we propose a monolithic integrated poly(dimethylsiloxane) (PDMS)/poly(methyl methacrylate) (PMMA) photonic chip that monolithically integrates two photonic waveguide Bragg grating (WBG) blood glucose sensors, a photonic WBG pressure sensor array, four photonic WBG temperature sensors, a photonic Mach-Zehnder modulator (MZM) electrocardiogram (ECG) sensor, and a photonic Mach-Zehnder interferometer (MZI) sweat glucose sensor, together with an on-chip arrayed waveguide grating (AWG) demodulation unit. The experimental results demonstrate that the WBG glucose sensor operates stably from 0 to 2.3 mg/mL, the pressure sensor from 0 to 12 kPa, and the temperature sensor from 35 to 41°C. The MZM ECG sensor achieves a half-wave voltage of 1.6 V, with performance comparable to that of commercial systems. The MZI sweat glucose sensor offers a detection range of 0-0.2 mg/mL, a sensitivity of approximately 9.3595 mW/(mg/mL), and high linearity. With a miniature footprint of approximately 1 cm × 0.5 cm, this work offers a robust on-chip multiparameter sensing solution, paving the way for next-generation wearable continuous health monitoring.

Indexed as

Biosensing TechniquesBlood GlucosePolymersDimethylpolysiloxanesEquipment DesignHumansMonitoring, PhysiologicbaysilonBlood GlucoseDimethylpolysiloxanesPolymersblood glucoseelectrocardiogramintegrated photonic chipMach–Zehnder modulatorpressuretemperaturewaveguide Bragg grating

Identifiers

PMID42284480
PMCPMC13336876

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.