Evidence map›Paper›PMID 42284409›Full record

ArticleScience advances2026

Ready-to-load MHC-I nanoparticles for high-throughput T cell screening studies.

Hoang Anh T Phan, Soomin Eom, Daniel Hwang, Michael C Young, Shirley M Sun, Molly C Erdman, Yi Sun, Leena Mallik, Photis Rotsides, Mark M Painter and 3 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Hoang Anh T PhanCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0001-6488-0404
Soomin EomCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0009-0006-3526-4518
Daniel HwangCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-6071-8271
Michael C YoungCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-8420-2149
Shirley M SunCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0009-0007-6764-5750
Molly C ErdmanCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0009-0007-3658-5900
Yi SunCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-7821-4346
Leena MallikCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.
Photis RotsidesCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-2985-9954
Mark M PainterDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID 0000-0002-0180-2748
E John WherryDepartment of Systems Pharmacology and Translational Therapeutics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID 0000-0003-0477-1956
Dimitri S MonosDepartment of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-4065-0908
Nikolaos G SgourakisCenter for Computational and Genomic Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0003-3655-3902

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

MHC-I proteins present epitopic peptides to CD8

Indexed as

CD8-Positive T-LymphocytesHigh-Throughput Screening AssaysHistocompatibility Antigens Class INanoparticlesT-LymphocytesAntigen PresentationHumansLymphocyte ActivationPeptidesReceptors, Antigen, T-CellHistocompatibility Antigens Class IPeptidesReceptors, Antigen, T-Cell

Identifiers

PMID42284409
PMCPMC13262618

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.