Evidence map›Paper›PMID 42284398›Full record

ArticleScience advances2026

Transcription factor Tono mediates histone H3K4 trimethylation to regulate endoreplication through transcriptional reprogramming.

Hao Li, Yingying Song, Mengge Guo, Dongqin Yuan, Xing Zhang, Tingting Cheng, Jian Peng, Ling Wei, Qingyou Xia, Daojun Cheng and 1 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hao LiIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0009-0009-9155-3105
Yingying SongIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Mengge GuoIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Dongqin YuanIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Xing ZhangIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0009-0009-8522-2553
Tingting ChengIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.
Jian PengIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-7858-0709
Ling WeiSchool of Life Sciences, Southwest University, Chongqing 400715, China.ORCID 0000-0002-7461-9397
Qingyou XiaIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-9263-2886
Daojun ChengIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-4612-0046
Wenliang QianIntegrative Science Center of Germplasm Creation in Western China (CHONGQING) Science City, Biological Science Research Center, Southwest University, Chongqing 400715, China.ORCID 0000-0002-2222-6997

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoreplication is a cell cycle variant that involves multiple rounds of DNA replication without cell division, resulting in enlarged cells and organs. Here, we combined the

Indexed as

DNA ReplicationDrosophila ProteinsHistonesInsect ProteinsTranscription FactorsTranscription, GeneticAnimalsBombyxEpigenesis, GeneticGene Expression ProfilingMethylationSalivary GlandsDrosophila Proteinshistone H3 trimethyl Lys4HistonesInsect ProteinsTranscription Factors

Identifiers

PMID42284398
PMCPMC13262622

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.