Evidence map›Paper›PMID 42284395›Full record

ArticleScience advances2026

Bacteriophages hijack 2',3'-cNMPs to enhance transposase-mediated phage DNA integration in

Binbin Cui, Xiwen Ling, Ganjin Peng, Quan Guo, Xiaohan Kong, Rixiang Wang, Yingfei Ma, Pujuan Deng, Hua Cai, Xiaoxue Wang and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Binbin CuiPharmacy Department, Ningbo Medical Center Lihuili Hospital, Ningbo 315046, China.ORCID 0009-0007-9389-4398
Xiwen LingSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Ganjin PengSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0009-0000-3528-1023
Quan GuoSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.
Xiaohan KongSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0003-2139-0741
Rixiang WangPharmacy Department, Ningbo Medical Center Lihuili Hospital, Ningbo 315046, China.
Yingfei MaState Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.ORCID 0000-0002-2563-5390
Pujuan DengDepartment of Biochemistry, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-3197-3126
Hua CaiSino-French Hoffmann Institute, School of Basic Medical Science, Guangzhou Medical University, Guangzhou 511495, China.ORCID 0000-0002-6697-652X
Xiaoxue WangGuangdong Key Laboratory of Marine Materia Medica, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.ORCID 0000-0002-7257-1916
Yinyue DengSchool of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Sun Yat-sen University, Shenzhen 518107, China.ORCID 0000-0003-1511-0870

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nucleotide second messengers are widely used to mediate the physiology and antiphage immunity in bacteria. It was revealed that 2',3'-cAMP/2',3'-cGMP synthetase activity is required for immune response in plants. However, it remains unclear whether 2',3'-cNMPs are involved in the interactions between bacteria and phages. Here, we report that 2',3'-cNMPs, which are synthesized by RnaA and degraded by A1S_2339, A1S_0249, and A1S_2666, play critical roles in the modulation of the physiology of

Indexed as

Acinetobacter baumanniiBacteriophagesDNA, ViralTransposasesVirus IntegrationBacterial ProteinsPromoter Regions, GeneticBacterial ProteinsDNA, ViralTransposases

Identifiers

PMID42284395
PMCPMC13262624

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.