Evidence map›Paper›PMID 42284330›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2026

Heterotypic intercellular adhesion tunes efficiency of cell-on-cell migration.

Chandrashekar Kuyyamudi, Suhrid Ghosh, Cassandra G Extavour

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Chandrashekar Kuyyamudi *Department of Organismic and Organismic Biology, Harvard University, Cambridge, MA 02138.
Suhrid Ghosh *Department of Organismic and Organismic Biology, Harvard University, Cambridge, MA 02138.ORCID 0000-0001-6110-0169
Cassandra G ExtavourDepartment of Organismic and Organismic Biology, Harvard University, Cambridge, MA 02138.ORCID 0000-0003-2922-5855

Funding

DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Harvard | Faculty of Arts and Sciences, Harvard University (FAS) n/aHHMI (HHMI) n/aNIH HHS P40 OD010949NSF (NSF) DMS-1764269
6 · The paper itself

Abstract

Cell migration across epithelial barriers occurs in diverse developmental, immunological, and pathological contexts. Here, we investigate the contribution of heterotypic adhesion between migrating cells and epithelial "substrate" cells to transepithelial migration. Using an in silico model inspired by the migration of primordial germ cells across the midgut epithelium in the

Indexed as

Cell AdhesionCell MovementDrosophila melanogasterAnimalsCadherinsDrosophila ProteinsGerm CellsModels, BiologicalCadherinsDrosophila ProteinsCellular Potts modelCompuCell3DE-cadheringerm cell migrationintercellular adhesion

Identifiers

PMID42284330
PMCPMC13273321

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.