Evidence map›Paper›PMID 42284312›Full record

ArticlePLOS global public health2026

Utility of sentinel surveillance as an early warning system for emerging pathogens in a low-resource setting: Correlations of dengue, chikungunya, Zika, and COVID-19 trends between sentinel and passive surveillance systems in Puerto Rico, 2012-2023.

Alfonso C Hernandez-Romieu, Zachary J Madewell, Mark Delorey, Hannah R Volkman, Liliana Sanchez-Gonzalez, Vanessa Rivera-Amill, Diego Sainz de la Peña, Jorge Bertrán-Pasarell, Verónica M Frasqueri-Quintana, Jomil Torres Aponte and 11 more

Abstract read
In one paragraph

Article in PLOS global public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Economic burden of dengue in Puerto Rico, 2010-2023.Infectious diseases of poverty · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Alfonso C Hernandez-RomieuDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0003-3653-607X
Zachary J MadewellDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0002-5667-9660
Mark DeloreyDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, Colorado, United States of America.
Hannah R VolkmanDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0001-7274-9641
Liliana Sanchez-GonzalezDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0001-8289-8587
Vanessa Rivera-AmillPonce Health Sciences University/Ponce Research Institute, Ponce, Puerto Rico.ORCID https://orcid.org/0000-0003-4810-0871
Diego Sainz de la PeñaAuxilio Mutuo Hospital, San Juan, Puerto Rico.
Jorge Bertrán-PasarellAuxilio Mutuo Hospital, San Juan, Puerto Rico.
Verónica M Frasqueri-QuintanaPonce Health Sciences University/Ponce Research Institute, Ponce, Puerto Rico.ORCID https://orcid.org/0000-0002-9566-1404
Jomil Torres AponteDivision of Epidemiology and Research, Puerto Rico Department of Health, San Juan, Puerto Rico.
Melissa Marzan-RodríguezDivision of Epidemiology and Research, Puerto Rico Department of Health, San Juan, Puerto Rico.
Aidsa RiveraDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Olga LorenziDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Carla P Espinet-CrespoDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Yashira MaldonadoDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0002-6958-250X
Roberta Lugo-RoblesDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0001-8918-2338
Gilberto A SantiagoDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.ORCID https://orcid.org/0000-0002-8864-9503
Janice Perez-PadillaDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Jorge L Muñoz-JordánDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Gabriela Paz-BaileyDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.
Laura E AdamsDivision of Vector-Borne Diseases, Centers for Disease Control and Prevention, San Juan, Puerto Rico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The representativeness and timeliness of sentinel surveillance for endemic and emerging arboviral and respiratory diseases in low-resource settings are understudied. We compared laboratory-confirmed epidemic dengue, non-epidemic dengue, Zika, chikungunya, and COVID-19 (pre-Omicron and Omicron periods) cases reported in Puerto Rico's Sentinel Enhanced Dengue Surveillance System (SEDSS) with island-wide trends reported by the Department of Health's passive disease surveillance system (PADSS). We plotted trends over time to assess representativeness and used lagged cross-correlations to determine whether SEDSS reporting preceded PADSS. SEDSS trends were representative of island-wide trends for all pathogens. SEDSS preceded reporting in PADSS by up to three, eight, and two weeks for epidemic dengue, Zika, and pre-Omicron COVID-19, respectively. Increasing case trends for chikungunya occurred at broadly similar times in both systems, while temporal concordance was lower for non-epidemic dengue. In Puerto Rico, sentinel surveillance was representative of island-wide trends and could provide early warning for dengue epidemics and emerging diseases, such as Zika and COVID-19.

Identifiers

PMID42284312
PMCPMC13262841

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.