Evidence map›Paper›PMID 42284212›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2026

Population Viral Load Suppression and Associated Factors in Tanzania: Findings From 2 Sequential Tanzania HIV Impact Surveys of 2016-2017 and 2022-2023.

Abbas Ismail, Prosper Njau, Alice Wang, Alexander Kailembo, Samwel Sumba, Baraka Revocatus, Eliezer Taluka, Mary Mayige, Tepa Nkumbula, Elias Bukundi and 15 more

Abstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Abbas IsmailDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.ORCID 0000-0001-9986-0200
Prosper NjauNational AIDS, STIs and Hepatitis Control Programme, Dodoma, Tanzania.
Alice WangDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.ORCID 0000-0001-9519-3842
Alexander KailemboDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.ORCID 0000-0002-3439-8171
Samwel SumbaTanzania Commission for AIDS, Dodoma, Tanzania.
Baraka RevocatusBugando Medical Centre, Mwanza, Tanzania.ORCID 0000-0002-7617-6454
Eliezer TalukaICAP at Columbia University, Dar es Salaam, Tanzania.
Mary MayigeNational Institute of Medical Research, Dar es Salaam, Tanzania.
Tepa NkumbulaICAP at Columbia University, Dar es Salaam, Tanzania.
Elias BukundiDepartment of Epidemiology and Biostatistics, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.ORCID 0000-0002-7374-7688
Haji Faki FakiZanzibar Integrated HIV, Hepatitis, Tuberculosis, and Leprosy Programme, Unguja, Zanzibar.
Emilian KarugendoNational Bureau of Statistics, Dodoma, Tanzania.
Fahima IssaOffice of Chief Government Statistician, Unguja, Zanzibar.
Nyambura MoremiMinistry of Health Tanzania, Public Health Laboratory, Dar es Salaam, Tanzania.ORCID 0000-0002-5303-1156
Malewo OptatusDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.
Geofrey MchauDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.ORCID 0000-0002-4640-0486
Rebecca L LawsDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Atlanta, GA; and.
Divya PatelDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Atlanta, GA; and.
Haruka MaruyamaICAP at Columbia University, Dar es Salaam, Tanzania.
Wafaa El-SadrICAP at Columbia University, New York, NY.ORCID 0000-0003-3735-9781
Shannon M FarleyICAP at Columbia University, New York, NY.
George MgomellaDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.ORCID 0000-0002-9525-7612
Mahesh SwaminathanDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.
Sarah E PorterDivision of Global HIV and TB, U.S. Centers for Diseases Control and Prevention, Dar es Salaam, Tanzania.
Jerome KamwelaTanzania Commission for AIDS, Dodoma, Tanzania.ORCID 0000-0002-8810-5565

Funding

CGH CDC HHS NU2GGH002173Intramural CDC HHS CC999999U.S. President's Emergency Plan for AIDS Relief # NU2GGH0001226 and NU2GGH002173
6 · The paper itself

Abstract

backgroundAntiretroviral therapy improves outcomes for people living with HIV (PLHIV) and prevents transmission through viral load suppression (VLS). To evaluate progress toward HIV epidemic control, VLS prevalences and correlates among PLHIV were analyzed from Tanzania HIV Impact Assessment Surveys (THIS), independent, cross-sectional using stratified-cluster design, conducted in 2016-2017 (S1) and 2022-2023 (S2).

methodsParticipants 15 years and older provided consent, completed an interviewer-administered questionnaire, and tested for HIV using the national rapid testing algorithm. HIV-positive specimens were tested for viral load. Prevalence of population VLS (<1000 copies/mL) was determined irrespective of HIV-knowledge or antiretroviral therapy status. Modified Poisson Regression Model was used. We reported percentages (%) and adjusted prevalence ratios with 95% confidence intervals (CIs) accounting for complex survey design.

resultsWe analyzed data from 1830 PLHIV in S1 and 1849 in S2. Population VLS prevalence increased by 26.1% (95% CI: 22.1 to 30.2, P < 0.0001) between surveys. In both surveys, women were more likely to experience VLS [S1: 1.43 (95% CI: 1.25 to 1.63), S2: 1.15 (95% CI: 1.06 to 1.24)] than men. In both surveys, PLHIV 35 years and older were more likely to experience VLS than those 15-24 years, [S1 35-49 years: 1.46 (95% CI: 1.13 to 1.90), 50 years and older: 1.69 (95% CI: 1.28 to 2.23), and S2 35-49 years: 1.31 (95% CI: 1.06 to 1.62), 50 years and older: 1.42 (95% CI: 1.15 to 1.76)].

conclusionTanzania has made progress toward HIV epidemic control, as evidenced by the significant increase in VLS prevalence in 6 years. Targeted sex-age strategies are essential for HIV epidemic control.

Indexed as

Anti-HIV AgentsHIV InfectionsViral LoadAdolescentAdultCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrevalenceSurveys and QuestionnairesTanzaniaYoung AdultAnti-HIV Agentsantiretroviral therapyHIVTanzaniaviral load

Identifiers

PMID42284212
PMCPMC13507933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.