Evidence map›Paper›PMID 42284210›Full record

ArticleHuman vaccines & immunotherapeutics2026

Causal associations between antibody-mediated immune responses to infectious agents and cardiovascular inflammatory diseases: A Mendelian randomization study based on UK Biobank and FinnGen.

Qi Huang, Wanqian Pan, Shikun Sun, Weixiang Chen, Jia Lin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Qi HuangDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, P. R. China.
Wanqian PanDepartment of Cardiovasology, The First Affiliated Hospital of Hainan Medical University, Haikou, P. R. China.
Shikun SunDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, P. R. China.
Weixiang ChenDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, P. R. China.
Jia LinDepartment of Cardiology, The First Affiliated Hospital of Soochow University, Suzhou, P. R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A two-sample Mendelian randomization study was performed to evaluate causal associations between 46 pathogen-specific antibodies and six cardiovascular inflammatory diseases: myocarditis, pericarditis, endocarditis, coronary atherosclerosis (CAS), polyarteritis nodosa (PAN), and giant cell arteritis (GCA). Antibody data came from UK Biobank, diseases data came from FinnGen. Instrumental variables were selected using strict (

Indexed as

Antibodies, ViralCardiovascular DiseasesBiological Specimen BanksFemaleHumansMaleMendelian Randomization AnalysisMyocarditisUnited KingdomAntibodies, ViralAntibody-mediated immune responses to infectious agentscoronary atherosclerosisgiant cell arteritisMendelian randomizationmyocarditis

Identifiers

PMID42284210
PMCPMC13274133

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.