Evidence map›Paper›PMID 42283991›Full record

ArticleApplied biochemistry and biotechnology2026

Isolation, Structural Characterization, and Potent Leishmanicidal, Anti-Cancer, and Anti-Microbial Activities of a New Diosgenin Glycoside from Malvastrum coromandelianum.

Sheema, Qaisar Jamal, Karishma Bibi, Syed Adnan Ali Shah, Hammad Ismail, Muhammad Rashid, Salman Zafar

Abstract read
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Article in Applied biochemistry and biotechnology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

SheemaInstitute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Pakistan.
Qaisar JamalInstitute of Zoological Sciences, University of Peshawar, Peshawar, 25120, Pakistan.
Karishma BibiInstitute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Pakistan.
Syed Adnan Ali ShahFaculty of Pharmacy, Universiti Teknologi Mara, Shah Alam, 40450, Malaysia.
Hammad IsmailDepartment of Biochemistry and Biotechnology, University of Gujrat, Gujrat, 50700, Pakistan.
Muhammad RashidDepartment of Biosciences, Grand Asian University of Sialkot, Sialkot, 51310, Pakistan.
Salman ZafarInstitute of Chemical Sciences, University of Peshawar, Peshawar, 25120, Pakistan. salmanzafar@uop.edu.pk.

Funding

Council for Scientific and Industrial Research, South Africa SW(HO)/DRSI-6/2025/44/07
6 · The paper itself

Abstract

The ever-evolving microbes have posed serious threats to human health for the past couple of decades, which has left the synthetic antibiotics useless against certain microbes. This has led to a paradigm shift towards discovery of benign bioactive materials from natural sources, especially plants. Phytochemical studies were therefore carried out on Malvastrum coromandelianum, resulting in the isolation of a new diosgenin glycoside, salmanoside (1), along with two known metabolites, identified as digitonin (2) and 7-hydroxycoumarin (3). Compound 1 was found to be a significant inhibitor of Leishmania tropica promastigotes (IC

Indexed as

Anti-Infective AgentsAntineoplastic AgentsAntiprotozoal AgentsDiosgeninGlycosidesAnimalsAnti-Bacterial AgentsHeLa CellsHumansStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsAntineoplastic AgentsAntiprotozoal AgentsDiosgeninGlycosidesAnti-cancerAnti-microbialDiosgenin glycosideLeishmanicidalMalvastrum coromandelianumSalmanoside

Identifiers

PMID42283991

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.