Evidence map›Paper›PMID 42283911›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2026

Diagnostic techniques and detailed assessment of fetal intraspinal lipoma: a prospective study.

Benzhang Tao, Gan Gao, Yang Li, Cheng Chen, Guangyu Qiao, Tao Zhu

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Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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6 authors.

Benzhang Tao *Department of Neurosurgery, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, China.
Gan Gao *Senior Department of Neurosurgery, The First Medical Center of PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Yang LiDepartment of Critical Care Medicine, Chinese PAP Beijing Corps Hospital, Beijing, China.
Cheng ChenSenior Department of Neurosurgery, The First Medical Center of PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
Guangyu QiaoSenior Department of Neurosurgery, The First Medical Center of PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. qgy301@126.com.
Tao ZhuDepartment of Neurosurgery, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, China. zhutao5@126.com.ORCID 0000-0002-6103-535X

Funding

Capital Funds for Health Improvement and Research CFH2022-2-5022National Key Research and Development Program of China 2022YFA1105501National Key Research and Development Program of China 2022YFC2703304National Key Research and Development Program of China 2025YFC2511500
6 · The paper itself

Abstract

purposeTo explore the technical methods and advantages of prenatal diagnosis of fetal intraspinal lipomas.

methodsThis was a prospective study. From August 2018 to August 2024, 315 fetuses suspected of having spinal neural tube malformations after conducting prenatal ultrasound were treated at the Neurosurgery Outpatient Department of the First Medical Center of the PLA General Hospital. Fetal magnetic resonance imaging (MRI) examinations were performed within 72 h after the ultrasound diagnosis. A total of 186 singleton pregnancies where fetuses have already been born were selected. MRI was performed within 1 month after birth. Using postnatal MRI as the gold standard, 58 fetuses diagnosed with intraspinal lipoma through postnatal MRI were selected. The diagnostic coincidence rates of prenatal ultrasound and fetal MRI in the prenatal diagnosis of intraspinal lipomas were analyzed.

resultsPrenatal ultrasound correctly diagnosed 35 cases (35/58, 60.3%), and fetal MRI correctly diagnosed 49 cases (49/58, 84.5%). This difference was statistically significant (P = 0.004). Among the 58 cases of fetal intraspinal lipomas, 11 were of caudal type (11/58,19.0%), eight of dorsal type (8/58, 13.8%), ten of transitional type (10/58, 17.2%), 23 of mixed type (23/58, 39.7%), and six of lipoma myelomeningocele type (6/58, 10.3%). Among these, ten cases (10/58, 17.2%) were correctly diagnosed by prenatal ultrasound and 25 (25/58, 43.1%) using fetal MRI. This difference was statistically significant (P = 0.002).

conclusionsFetal MRI can accurately diagnose intraspinal lipomas and has diagnostic value for different types of intraspinal lipomas.

Indexed as

LipomaPrenatal DiagnosisSpinal Cord NeoplasmsSpinal NeoplasmsUltrasonography, PrenatalAdultFemaleHumansMagnetic Resonance ImagingMalePregnancyProspective StudiesFetusIntraspinal lipomaMagnetic resonance imagingPrenatal diagnosisTethered cord syndromeUltrasound

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.