Evidence map›Paper›PMID 42283868›Full record

ReviewBrain structure & function2026

Neurovariability as a signature of adaptive brain function.

Stephanie J Forkel, Lilit Dulyan, Kurt Schilling, Michel Thiebaut de Schotten

Abstract readReview
In one paragraph

Review in Brain structure & function, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stephanie J ForkelDonders Institute for Brain Cognition Behaviour, Radboud University, Nijmegen, the Netherlands. stephanie.forkel@gmail.com.ORCID http://orcid.org/0000-0003-0493-0283
Lilit DulyanDonders Institute for Brain Cognition Behaviour, Radboud University, Nijmegen, the Netherlands.ORCID http://orcid.org/0000-0002-8652-7828
Kurt SchillingVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID http://orcid.org/0000-0003-3686-7645
Michel Thiebaut de SchottenBrain Connectivity and Behaviour Laboratory, Bordeaux, France.ORCID http://orcid.org/0000-0002-0329-1814

Funding

Microstructure and connectivity modeling from the cortex to the spinal cord in Multiple SclerosisK01EB032898 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SCHILLING, KURT G · 2022 to 2025
$630k
European Research Council 818521Nederlandse Organisatie voor Wetenschappelijk Onderzoek 015.021.008NIBIB NIH HHS K01 EB032898NIH HHS K01EB032898Stichting Dondersfonds 2401515
6 · The paper itself

Abstract

Neurovariability refers to the naturally occurring differences in brain structure and functional organisation across individuals. Rather than being noise, this variability reflects an adaptive feature of human neurobiology, supporting diversity, flexibility, learning, and resilience across evolution and lifespan. Here, we summarise the anatomical, functional, and evolutionary foundations of neurovariability, its relevance to health and disease, and the current limitations of methods for quantifying it. By understanding neurovariability as an emergent property of complex systems, we highlight its importance in advancing personalised neuroscience.

Indexed as

Adaptation, PhysiologicalBrainAnimalsBiological EvolutionHumansConnectivityEvolutionPersonalised neuroscienceVariabilityWhite matter

Identifiers

PMID42283868
PMCPMC13263195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.