Evidence map›Paper›PMID 42283819›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2026

Treatment and outcome of osteoporotic OF3 vertebral fractures: results from the prospective multicenter EOFTT study.

Sebastian Katscher, Bernhard W Ullrich, Felix C Kohler, Philipp Schenk, Klaus J Schnake, Georg Osterhoff, Max J Scheyerer, Gregor Schmeiser, Martin Bäumlein, Michael Scherer and 11 more

Abstract readMulticenter Study
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In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Sebastian KatscherInterdisciplinary Center for Spine and Neurotrauma, Sana Hospital, Borna, Germany. sebastian.katscher@sana.de.
Bernhard W UllrichDepartment of Trauma and Reconstructive Surgery, BG Trauma Center Bergmannstrost gGmbH, Halle, Germany.
Felix C KohlerDepartment of Trauma, Hand and Reconstructive Surgery, University Hospital, Jena, Germany.
Philipp SchenkInnovationhub for Musculoskeletal Surgery Halle, BG Trauma Center Bergmannstrost gGmbH, Halle (Saale), Germany.
Klaus J SchnakeCenter of Spinal and Skoliosis Surgery, Malteser Hospital St. Marien , Erlangen, Germany.
Georg OsterhoffDepartment of Traumatology and Orthopedics, BG Trauma Center, Berlin, Germany.
Max J ScheyererDepartment of Orthopedics and Traumatology, University Hospital, Cologne, Germany.
Gregor SchmeiserDepartment of Spine Surgery, Schoen Hospital Hamburg- Eilbek, Hamburg, Germany.
Martin BäumleinCenter of Orthopedics and Trauma Surgery, University Hospital, Giessen and Marburg, Germany.
Michael SchererSpine Surgery, Arabella Hospital, Munich, Germany.
Michael MüllerDepartment of Orthopedics and Trauma Surgery, University Medical Center Schleswig-Holstein, Kiel, Germany.
Kai SprengelDepartment of Trauma Surgery, University Hospital, Zurich, Switzerland.
Katja LiepoldDepartment of Spine Surgery, Thuringia Hospital Georgius Agricola, Saalfeld, Germany.
Simon SchrammDepartment of Trauma Surgery, University Hospital, Erlangen, Germany.
Christopher BaronSpinal Cord Unit, BG Trauma Center, Tubingen, Germany.
Holger SiekmannDepartment of Orthopedics and Traumatology, Hospital, Doebeln, Germany.
Falko SchwarzDepartment of Neurosurgery, University Hospital Friedrich Schiller, Jena, Germany.
Alexander FranckDepartment of Orthopedics and Trauma Surgery, Regiomed Hospital, Coburg, Germany.
Volker ZimmermannCenter of Trauma Surgery and Orthopedics, Hospital, Traunstein, Germany.
Dina W WiersbickiDepartment of Trauma Surgery, Orthopedics, Hand- and Reconstructive Surgery, University Hospital, Leipzig, Germany.
Ulrich J A SpieglDepartment of Trauma and Orthopedic Surgery, Hospital Munich Harlaching, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe number of osteoporotic thoracolumbar vertebral fractures (OVCF) is steadily increasing. Incomplete burst type fractures of type OF3 represent a significant proportion of OVCF. The aim of this study is therefore to evaluate the different treatment modalities of OF3 fractures. MATERIAL/

methodsA prospective multicenter evaluation of the osteoporotic fracture classification, treatment score and therapy recommendations (EOFTT) was conducted from 2017 to 2020. Patients with OF3 fractures and a minimum follow-up of 6 weeks were included. The exclusion criteria were dementia, malignancies and a history of surgical stabilization or fusion in the fracture region. Before treatment (TD, day of treatment decision) and at last follow-up (FU), the OF score and the following parameters were collected: VAS, Timed Up & Go test (TuG), ODI, Eq. 5D 5 L and complications.

resultsA total of 218 patients with OF3 fractures and mean age of 75 ± 10 years (range 41-96, female 73%) were examined. Conservative treatment was performed in 73 (33%) patients (VAS 4,3, TuG 19´´, ODI 0,55, Eq. 5D 5 L 0,51). Surgical treatment strategies were mainly performed as isolated cementaugmentation (n = 65; 30% - VAS 6,9, TuG 26´´, ODI 0.69, Eq. 5D 5 L 0,33) and short-segment hybrid stabilization (n = 80, 37% - VAS 6,8, TuG 31´´, ODI 0,74, Eq. 5D 5 L 0,64). The time points for assement of the parameters before and after treatment were the day of treatment decision TD (before) and the last available follow up FU (minimum 6 weeks, maximum 12 months - mean FU in the conservative group 6 ± 5 months, mean FU in surgical group 8 ± 5 months). Surgically treated patients reported significantly worse pain (p < 0.001), reduced mobility (TuG p < 0.001) and higher functional limitations (ODI, p < 0.001) before treatment. Patients benefited from all main treatment strategies and improved significantly (p < 0.001), with surgically treated patients showing greater improvement following hybrid stabilization compared with augmentation alone. General complications occured more frequently in surgical group (22,4% vs. 2,7%), specific surgical complications occured in 5/145 patients (3,5%) with 3/145 requiring revision surgery (2,1%).

conclusionOF3 fractures respond to both conservative and surgical treatment. Isolated cementaugmentation and percutaneous bisegmental hybrid stabilization are the main surgical strategies. High OF scores including severe pain and limited mobility are indications for surgical intervention. All treatment strategies showed significant improvement. Greater improvement was observed in patients treated with hybrid stabilization than with isolated cementaugmentation, which may be important from a functional point of view.

Indexed as

Lumbar VertebraeOsteoporotic FracturesSpinal FracturesThoracic VertebraeAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeEOFTTOF classificationOsteoporosisOsteoporotic fractureThoracolumbar spineVertebral body fracture

Identifiers

PMID42283819

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