ArticleJACC. Case reports2026
Simultaneous Valve-in-Valve TAVR With Bioprosthetic Valve Fracture and Left Atrial Appendage Closure for Refractory Left Atrial Thrombus.
Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Pushing the Limits of Concomitant Structural Intervention: How Far Is Too Far?JACC. Case reports · 2026Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPersistent left atrial appendage thrombus complicates structural intervention when anticoagulation is limited by bleeding risk. CASE SUMMARY: A 74-year-old man with prior surgical aortic and mitral bioprostheses presented with heart failure from severe bioprosthetic aortic stenosis and persistent left atrial appendage thrombus despite 6 months of anticoagulation. Because of recent gastrointestinal bleeding and progressive valve obstruction, the heart team selected a single-session strategy using Sentinel cerebral embolic protection. Valve-in-valve transcatheter aortic valve replacement was performed first, followed by bioprosthetic valve fracture confirmed by balloon pressure drop, waist release, and gradient reduction. Left atrial appendage closure was then performed with a Watchman FLX Pro device, trapping residual thrombus. Retrieved cerebral protection filters contained thrombotic debris, and the patient recovered without neurologic complications. DISCUSSION: In selected high-risk patients, simultaneous valve intervention and thrombus-exclusion left atrial appendage closure under cerebral protection may reduce cumulative procedural and anticoagulation-related risks.
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