Evidence map›Paper›PMID 42283679›Full record

ArticleJACC. Case reports2026

Recurrent Coronary Restenosis in Takayasu Arteritis: A Stent-Sparing Strategy.

Abdallah Rayyan, Aseed Mestarihi, Khanjan Shah, Matheen Khuddus

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Abdallah RayyanGraduate Medical Education, Internal Medicine Residency Program, University of Central Florida College of Medicine/HCA Florida North Florida Hospital, Gainesville, Florida, USA. Electronic address: Abdallah.rayyan@outlook.com.
Aseed MestarihiGraduate Medical Education, Internal Medicine Residency Program, University of Central Florida College of Medicine/HCA Florida North Florida Hospital, Gainesville, Florida, USA.
Khanjan ShahDivision of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, Florida, USA.
Matheen KhuddusDepartment of Cardiology, The Cardiac and Vascular Institute, Gainesville, Florida, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronary involvement in Takayasu arteritis is uncommon but associated with high rates of in-stent restenosis and challenging revascularization. CASE SUMMARY: A 22-year-old woman with Takayasu arteritis and congenital antithrombin III deficiency presented with non-ST-segment elevation myocardial infarction due to severe ostial right coronary artery in-stent restenosis after multiple prior percutaneous interventions. Intravascular ultrasound confirmed significant neointimal hyperplasia. A stent-sparing strategy using excimer laser coronary atherectomy, cutting balloon angioplasty, and paclitaxel drug-coated balloon under intravascular ultrasound guidance was performed with bivalirudin anticoagulation. Final angiography demonstrated TIMI 3 flow with significant luminal gain. DISCUSSION: Recurrent restenosis in Takayasu arteritis represents a major therapeutic challenge. This case highlights the role of multimodal, stent-avoidant strategies and individualized anticoagulation in complex inflammatory vasculopathy with concomitant thrombophilia. TAKE-HOME MESSAGES: Recurrent in-stent restenosis in Takayasu arteritis reflects ongoing vascular inflammation and requires strategies beyond repeat stenting. A stent-sparing, intravascular imaging-guided approach using laser atherectomy and drug-coated balloon can effectively treat refractory restenosis while minimizing additional stent burden.

Indexed as

autoimmunecardiovascular diseasecoronary angiographydrug-coated balloonintravascular ultrasoundmyocardial revascularizationpercutaneous coronary interventionrheumatic heart disease

Identifiers

PMID42283679
PMCPMC13480237

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.