Evidence map›Paper›PMID 42283387›Full record

ArticleAngewandte Chemie (International ed. in English)2026

Antiaromaticity-Driven Enhancement of Single-Molecule Electrical Conductance by s-Indacene Molecular Bridges.

Ching-Piao Chu, Yuki Hanamura, Tatsuhiko Ohto, Seiya Maeda, Ryo Yamada, Siao-Lei Yu, Yen-Ju Cheng, Hirokazu Tada, Yoshito Tobe

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In one paragraph

Article in Angewandte Chemie (International ed. in English), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ching-Piao ChuDepartment of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Yuki HanamuraGraduate School of Engineering Science, The University of Osaka, Toyonaka, Japan.
Tatsuhiko OhtoGraduate School of Engineering Science, The University of Osaka, Toyonaka, Japan.ORCID https://orcid.org/0000-0001-8681-3800
Seiya MaedaGraduate School of Engineering Science, The University of Osaka, Toyonaka, Japan.
Ryo YamadaGraduate School of Engineering Science, The University of Osaka, Toyonaka, Japan.ORCID https://orcid.org/0000-0003-1761-0713
Siao-Lei YuDepartment of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Yen-Ju ChengDepartment of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.
Hirokazu TadaGraduate School of Engineering Science, The University of Osaka, Toyonaka, Japan.
Yoshito TobeDepartment of Applied Chemistry, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.ORCID https://orcid.org/0000-0002-1795-5829

Funding

Ministry of Education (MOE), TaiwanNational Science and Technology Council, Taiwan 113-2113-M-A49-015-MY3National Science and Technology Council, Taiwan 114-2113-M-A49-009SPROUT Project-Center for Emergent Functional Matter Science of National Yang Ming Chiao Tung UniversityYushan Fellow Program by MOE, Taiwan JP22H00315Yushan Fellow Program by MOE, Taiwan JP25K22244Yushan Fellow Program by MOE, Taiwan JSPS KAKENHIYushan Fellow Program by MOE, Taiwan MOE-113-YSFMS-0010-001-P1
6 · The paper itself

Abstract

High electrical conductance of antiaromatic molecules compared with aromatic counterparts at the single-molecule level has been a topic of controversy, with only a few previous experimental proofs. We synthesized length-matched molecular wires incorporating 12 π-electron antiaromatic s-indacene (Ind) and 14 π-electron aromatic benzodithiophene (BDT) cores with different anchoring modes and measured the single-molecule electrical conductance (SMEC) by scanning tunneling microscopy-break junction method, validating that antiaromatic cores significantly enhance the conductance. For the diagonally anchored systems, the antiaromatic Ind derivative exhibits SMEC approximately 10 times higher than that of its aromatic BDT analogue, thanks to the cooperative effects of a linear conjugation pathway and the narrow gap between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) that brings favorable frontier molecular orbital (FMO) alignment with the electrode Fermi level. Notably, for the horizontally anchored systems, the Ind derivative exhibits SMEC 2.8 times higher than that of its BDT counterpart, as its antiaromaticity-driven FMO alignment overtakes the cross-conjugation pathway. Additionally, introduction of electron-withdrawing trifluoromethyl groups to the Ind core shifts the LUMO closer to the Fermi level, resulting in 1.5 times higher conductance. These results definitively demonstrate the enhancement of SMEC driven by antiaromaticity.

Indexed as

antiaromaticityaromaticityHOMO–LUMO gapmolecular electronicssingle‐molecule conductance

Identifiers

PMID42283387
PMCPMC13452568

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.