Evidence map›Paper›PMID 42283335›Full record

ArticleThe plant genome2026

A chromosome-level genome assembly of Solanum brevicaule (PI 473011) Y1-5, a wild potato relative with robust resistance to potato cyst nematodes.

Senthilkumar Shanmugavel, Shengwei Hu, Huijun Yang, Shiyan Chen, John Bamberg, Dongyan Zhao, Bhoja R Basnet, Craig T Beil, Moira Sheehan, Vidyasagar Sathuvalli and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The plant genome, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Senthilkumar ShanmugavelHermiston Agricultural Research and Extension Centre, Oregon State University, Hermiston, Oregon, USA.
Shengwei HuPlant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0009-0001-5888-3040
Huijun YangUSDA-ARS Robert W. Holley Center for Agriculture and Health, Ithaca, New York, USA.
Shiyan ChenPlant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-6730-8216
John BambergUSDA-ARS, US Potato Genebank, Sturgeon Bay, Wisconsin, USA.ORCID https://orcid.org/0000-0001-6102-7846
Dongyan ZhaoBreeding Insight, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-2080-8416
Bhoja R BasnetBreeding Insight, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-1693-4807
Craig T BeilBreeding Insight, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-1756-9987
Moira SheehanBreeding Insight, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-3400-2165
Vidyasagar SathuvalliHermiston Agricultural Research and Extension Centre, Oregon State University, Hermiston, Oregon, USA.ORCID https://orcid.org/0000-0001-5727-9987
Xiaohong WangPlant Pathology and Plant-Microbe Biology Section, School of Integrative Plant Science, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0003-1790-4084

Funding

USDA-NIFA SCRI 2022-51181-38450
6 · The paper itself

Abstract

Potato cyst nematodes (PCNs), Globodera rostochiensis and Globodera pallida, are globally recognized quarantine pests that can cause severe yield losses in potatoes (Solanum tuberosum L.) if left uncontrolled. Deploying host resistance remains the most effective, economical, and environmentally sustainable strategy for PCN control. The US Potato Genebank (USPG) maintains a rich collection of wild potato species, providing a valuable resource for discovering novel resistance to PCN. In this study, we identified a Solanum brevicaule clone (PI 473011; designated Y1-5) from the USPG that exhibits robust resistance to both PCN species. We sequenced the whole genome of Y1-5 using PacBio high-fidelity sequencing technology and generated a haplotype-resolved assembly, with genome sizes of 763.49 and 764.93 Mb for haplotypes 1 and 2, respectively. Repeat elements accounted for approximately 65% of the genome, while gene prediction identified 80,021 protein-coding genes. A comprehensive set of genes encoding nucleotide-binding and leucine-rich repeat (NLR) proteins-intracellular receptors that mediate disease resistance-was identified in the annotated genome. NLR genes were particularly enriched on chromosomes 4, 6, and 11. Importantly, Y1-5 was found to encode more coiled-coil-type NLRs than several previously sequenced wild Solanum clones. These findings suggest that Y1-5 may serve as a promising new source of resistance to potato diseases. Development of this genomic resource is valuable for understanding the mechanisms of PCN resistance and for supporting potato breeding efforts to develop varieties with durable nematode resistance.

Indexed as

Chromosomes, PlantDisease ResistanceGenome, PlantPlant DiseasesSolanumSolanum tuberosumAnimalsHaplotypesTylenchoidea

Identifiers

PMID42283335
PMCPMC13261804

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.