ArticleLower urinary tract symptoms2026
BOOI-Defined Obstruction Stratifies Early Outcomes After ThuLEP in Men With Detrusor Underactivity: A Retrospective Complete-Case Cohort Study.
Article in Lower urinary tract symptoms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundThe benefit of transurethral outlet surgery in men with benign prostatic enlargement/benign prostatic obstruction (BPE/BPO) and detrusor underactivity (DU) remains uncertain, particularly when bladder outlet obstruction (BOO) is not demonstrated by pressure-flow testing.
objectiveTo evaluate early outcomes after transurethral thulium laser enucleation of the prostate (ThuLEP) in men with DU and BPE/BPO-related voiding dysfunction, and to examine whether BOOI-defined obstruction status stratifies early postoperative improvement.
methodsWe retrospectively reviewed 189 ThuLEP records from a single centre and constructed a 100-patient complete-case cohort with interpretable preoperative pressure-flow studies and 3-month follow-up. DU was defined as bladder contractility index (BCI) < 100. BOO status was classified using bladder outlet obstruction index (BOOI) as definite BOO, equivocal BOO or no BOO. Functional, symptom, catheter-removal, anatomical and safety outcomes were compared descriptively across BOO strata.
resultsNinety-one patients (91.0%) had DU: 56 had definite BOO, 25 had equivocal BOO and 10 had no BOO. In the DU cohort, mean Q
conclusionsPreoperative BOOI-based stratification may help counsel men with DU regarding expected early functional improvement after ThuLEP. BOOI-defined no-BOO patients in this cohort were clinically selected after counseling, and the findings should be interpreted as exploratory because of the retrospective design, complete-case selection, short follow-up, and the small no-BOO subgroup.
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