SynthesisInfluenza and other respiratory viruses2026
Respiratory Syncytial Virus Transmission in Closed Community Settings That Include Children: A Systematic Review and Meta-Analysis.
Synthesis in Influenza and other respiratory viruses, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Respiratory Syncytial Virus Transmission in Closed Community Settings That Include Children: A Systematic Review and Meta-Analysis.Influenza and other respiratory viruses · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRespiratory syncytial virus (RSV) is a leading cause of severe respiratory infections in children and is predominantly acquired and spread in community settings such as households and early childhood education centres. This review aims to synthesise the available evidence on RSV transmission in closed community settings that include children, with a focus on secondary attack rates (SAR).
methodsWe conducted a systematic review informed by Cochrane guidelines. We searched Ovid Medline, Ovid Embase Classic and Embase, Ovid Global Health, Cochrane Library, Web of Science, and Scopus from inception to March 2025. Grey literature was searched through Google Scholar and relevant websites. We included articles reporting primary data on RSV SAR or other attack rates in closed community settings that included children aged under 18 years. Two reviewers independently screened articles, extracted data, and assessed study quality using a modified Newcastle-Ottawa Scale. Random-effects meta-analysis was performed for SAR and attack rates. Subgroup analyses explored outcomes by study design, study setting and participant age.
resultsA total of 38 articles were eligible and reported data from 30 unique study populations from 1956 to 2023 spanning 12 countries. Study settings included households (n = 19), early childhood education and care (n = 6) and residential care (n = 5). Pooled household SAR was 23.8% (95% CI: 16.5-30.0%) across all ages and 26.8% (95% CI: 15.5-38.2%) for children aged less than 5 years. Pooled outbreak attack rate among children in early childhood education and residential care was 59.2% (95% CI: 31.7-86.8%). There was substantial heterogeneity of methods, reporting and outcomes across studies.
conclusionRisk of RSV transmission in closed community settings that include children is substantial, yet current evidence is limited. Well-designed transmission studies, particularly in early childhood education and care settings, are needed to support disease prevention and control, and to optimise population-level modelling.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.