Evidence map›Paper›PMID 42283050›Full record

ArticleAnnals of neurosciences2026

Cerebrospinal Fluid Cytokine and Chemokine Profiles in Autoimmune Encephalitis: A Cross-sectional Study.

Arpna Srivastava, Rajesh Kumar Singh, Jyotirmoy Banerjee, Elavarasi A, Animesh Das, Bhargavi Ramanujam, Jasmine Parihar, Awadh Kishor Pandit, Vishnu V Y, Deepti Vibha and 3 more

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In one paragraph

Article in Annals of neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Arpna SrivastavaDepartment of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi, India.
Rajesh Kumar SinghDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0002-1969-9603
Jyotirmoy BanerjeeDepartment of Biophysics, All India Institute of Medical Sciences, New Delhi, India.
Elavarasi ADepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Animesh DasDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Bhargavi RamanujamDepartment of Neurology, PSRI Hospital, New Delhi, India.
Jasmine PariharDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Awadh Kishor PanditDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Vishnu V YDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.ORCID https://orcid.org/0000-0002-3654-8137
Deepti VibhaDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.
Sarat ChandraDepartment of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
M V Padma SrivastavaDepartment of Neurology, Paras Hospital, Gurugram, Haryana, India.
Manjari TripathiDepartment of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Autoimmune encephalitis (AE) is a major cause of acute and subacute neuropsychiatric syndromes. Purpose: While neuronal autoantibody testing aids diagnosis, results are often delayed or negative in seronegative cases. Cerebrospinal fluid (CSF) cytokine profiling may provide a rapid diagnostic adjunct. Methods: In this cross-sectional study, we analysed CSF from 43 AE patients (29 seronegative, 9 Results: All measured cytokines were significantly elevated in AE compared with controls ( Conclusions: CSF cytokines-particularly CXCL10, CXCL13, IL-6 and IL-13-are consistently elevated in AE and reflect shared intrathecal immune activation across antibody-positive and seronegative cases. These findings are exploratory, and cytokines are proposed as adjunctive immunological markers rather than standalone diagnostic tools.

Indexed as

Autoimmune encephalitisbiomarkerscerebrospinal fluidchemokinesCXCL10CXCL13cytokinesseronegative autoimmune encephalitis

Identifiers

PMID42283050
PMCPMC13249606

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