Evidence map›Paper›PMID 42282993›Full record

ArticleNew microbes and new infections2026

Prevalence of Transfusion-Transmitted Viruses Among Blood Donors at King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia (2019-2024).

Nariman Sindi, Osama A Alzahrani, Lamis M Alamoudi, Ahmad M Sait, Mansour Ali Alqahtani, Saad Abdullah Mufrrih, Ibrahim Mohammed Alqahtani, Nora Y Hakami, Fouad Mohammed Sait, Mohammed Alqahtani and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in New microbes and new infections, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Nariman SindiDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Osama A AlzahraniBlood Bank Laboratory, King Fahad Armed Forces Hospital, Jeddah, Saudi Arabia.
Lamis M AlamoudiDepartment of Statistics, Faculty of Science, King Abdulaziz University, Jeddah, 80200, Saudi Arabia.
Ahmad M SaitDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Mansour Ali AlqahtaniDepartment of Family Medicine, Armed Forces Hospitals Southern Region, Khamis, Mushayt, Saudi Arabia.
Saad Abdullah MufrrihDepartment of Family Medicine, Armed Forces Hospitals Southern Region, Khamis, Mushayt, Saudi Arabia.
Ibrahim Mohammed AlqahtaniDepartment of Family Medicine, Armed Forces Hospitals Southern Region, Khamis, Mushayt, Saudi Arabia.
Nora Y HakamiDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Fouad Mohammed SaitLaboratory Department, University Medical Services Center, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.
Mohammed AlqahtaniDepartment of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Najran University, Najran, Saudi Arabia.
Mohammed MufrrihDepartment of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, 21589, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To assess the prevalence, temporal trends, and diagnostic concordance of transfusion-transmitted viruses (TTVs) using combined serological and nucleic acid testing (NAT) in a large donor population in Jeddah, Saudi Arabia. Methods: This retrospective study analysed all blood donations screened from 2019 to 2024 at King Fahad Armed Forces Hospital, using serological assays and NAT. Prevalence estimates were calculated with 95% confidence intervals. Temporal trends were evaluated using generalised estimating equations logistic regression. Multivariable logistic regression identified predictors of Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) positivity. Diagnostic agreement between serology and NAT was assessed using Cohen's kappa statistic. Results: Among 48,151 donors, seroprevalence was 0.4% for HBsAg, 0.3% for HCV Ab, 0.1% for HIV Ab, and 0.02% for HTLV Ab. HBc Ab was detected in 4.7%. NAT identified HBV and HCV in 0.2% and 0.1%, respectively. Logistic regression showed a significant annual decline in HBsAg and NAT-HBV. Older age and non-Saudi nationality were linked to higher HBsAg and HCV positivity. Concordance between serology and NAT was substantial for HIV but negligible for HBV and HCV. Conclusions: TTVs rates are low and declining, but HBV/HCV concordance underscores the need for continued dual testing to ensure transfusion safety.

Indexed as

Blood donorsBlood transfusionHepatitis B virusNucleic acid amplification techniquesRetrospective studiesSaudi ArabiaSeroprevalence

Identifiers

PMID42282993
PMCPMC13251497

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.