Evidence map›Paper›PMID 42282917›Full record

ArticleEuropean journal of integrative medicine2026

Enduring versus curable: mixed-methods perspectives about pain among chiropractic patients.

Margaret D Whitley, Michele Maiers, Lara Hilton, Ryan S Wexler, Ian Coulter, Praise Iyiewuare, Gery Ryan

Abstract read
In one paragraph

Article in European journal of integrative medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Margaret D WhitleyRAND, Behavioral and Policy Sciences, 1776 Main St., Santa Monica, CA 90401, USA.ORCID 0000-0002-0530-1369
Michele MaiersRAND Research Across Complementary and Integrative Health (REACH) Center, 1776 Main St., Santa Monica, CA 90401, USA.ORCID 0000-0003-2370-4206
Lara HiltonUniversity of Southern California, Office of Behavioral Health, Division of Health Affairs, 3535 S. Figueroa St., Suite E202, Los Angeles, CA 90089, USA.ORCID 0000-0003-2375-8810
Ryan S WexlerHelfgott Research Institute, National University of Natural Medicine, 2220 SW 1st Ave., Portland, OR 97201, USA.ORCID 0000-0003-0121-2323
Ian CoulterRAND, Behavioral and Policy Sciences, 1776 Main St., Santa Monica, CA 90401, USA.ORCID 0000-0002-2352-1939
Praise IyiewuareRowan-Virtua School of Osteopathic Medicine, Department of Family Medicine, 42 Laurel Road, Stratford, NJ 08084, USA.ORCID 0000-0001-8619-9820
Gery RyanKaiser Permanente Bernard J Tyson School of Medicine, 98 S. Los Robles Ave., Pasadena, CA 91101, USA.ORCID 0000-0002-9256-9469

Funding

University of Michigan (UM) HEAL Initiative National K12 Clinical Pain Career Development Program (UM-HCPDP)K12NS130673 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Daniel J Clauw, Steven Edward Harte · 2022 to 2026
$12.5M
Systematic Review Core (SRC)/Ian D. CoulterU19AT007912 · NCCIH · RAND CORPORATION · PI COULTER, IAN DOUGLASS · 2013 to 2017
$8.5M
RAND REACH CenterU24AT012549 · NCCIH · RAND CORPORATION · PI COULTER, IAN DOUGLASS, HERMAN, PATRICIA M · 2023 to 2025
$6.2M
NCCIH NIH HHS U19 AT007912NCCIH NIH HHS U24 AT012549NINDS NIH HHS K12 NS130673
6 · The paper itself

Abstract

Introduction: Qualitative methods are fundamental for studying patient preferences, particularly to understand how people perceive and manage pain that is unresponsive to standard treatment. Yet there is limited literature describing how formative qualitative research can inform quantitative studies on chronic pain. Integrating patient perspectives from qualitative research helps ensure that quantitative protocols and pain measures are grounded in patients' lived experiences.This paper details how our team, as part of a center focused on appropriate care for spinal pain, collected qualitative data about how chiropractic patients perceived pain chronicity, and how we used these findings to inform a national quantitative study. Methods: In this exploratory sequential mixed methods study, we conducted 40 semi-structured interviews and deployed a mixed methods survey to 108 chiropractic patients with spinal pain. We conducted thematic analysis of the qualitative data, and we summarized those findings in a visual framework. The visual framework, in turn, informed the inclusion criteria and survey items for a quantitative, observational survey of 2,025 chronic pain patients from 125 chiropractic clinics in the United States. Results: Qualitative research revealed that many patients viewed chronic pain as permanent. Patients who defined chronicity this way shifted from seeking a cure to utilizing longer-term pain management and coping strategies; in this way, patients' understandings about chronicity influenced their care-seeking and satisfaction. This set of findings challenged our team's initial assumption that chronicity was primarily understood in terms of pain duration or intensity, and that all patients expected a cure. Conclusions: Qualitative findings shaped the methods and interpretation of our quantitative observational research. This process led to a conceptual framework of chronic pain, more informative surveys and a shared understanding of the diverse beliefs that drive care-seeking behaviors among chronic pain patients.

Indexed as

Chronic painComplementary and integrative healthcareMixed methodsSpinal pain

Identifiers

PMID42282917
PMCPMC13251724

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.