Evidence map›Paper›PMID 42282786›Full record

ArticlebioRxiv : the preprint server for biology2026

Molecular basis of competence for neural induction in the chick embryo.

Charlotte Colle, Vlad Arimia, Hui-Chun Lu, Claire Anderson, Leslie Dale, Claudio D Stern

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Charlotte ColleDepartment of Cell & Developmental Biology, University College London, Gower Street, London WC1E 6BT, U.K.ORCID 0000-0003-2062-2467
Vlad ArimiaDepartment of Cell & Developmental Biology, University College London, Gower Street, London WC1E 6BT, U.K.ORCID 0009-0008-1996-5693
Hui-Chun LuDepartment of Cell & Developmental Biology, University College London, Gower Street, London WC1E 6BT, U.K.ORCID 0000-0002-3075-4511
Claire AndersonDepartment of Cell & Developmental Biology, University College London, Gower Street, London WC1E 6BT, U.K.
Leslie DaleDepartment of Cell & Developmental Biology, University College London, Gower Street, London WC1E 6BT, U.K.ORCID 0000-0001-6174-6269
Claudio D SternDepartment of Cell & Developmental Biology, University College London, Gower Street, London WC1E 6BT, U.K.ORCID 0000-0002-9907-889X

Funding

EARLY EVENTS IN NEURAL AND HOMEOGENETIC INDUCTIONR01MH060156 · NIMH · UNIVERSITY COLLEGE LONDON · PI STERN, CLAUDIO D · 1999 to 2005
$867k
NIMH NIH HHS R01 MH060156Wellcome Trust
6 · The paper itself

Abstract

Competence is the capacity of a cell or tissue to respond to a specific inducing signal from a neighbouring tissue, by changing its fate in a specific direction. Neural induction is the process by which the epiblast of the early embryo responds to signals from the organizer (the tip of the primitive streak in amniotes) by forming a neural plate. Here we study why three regions of the early chick embryo lack competence to respond to neural induction by a grafted organizer: the outer anterior area opaca and the posterior area opaca at primitive streak stages (HH3

Identifiers

PMID42282786
PMCPMC13252060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.