Evidence map›Paper›PMID 42282750›Full record

ArticlebioRxiv : the preprint server for biology2026

Periplasmic detoxification of urate hydroperoxide underpins

Maxence S Vincent, Laurent Loiseau, Matthew Jones, Pierre Stocker, Khalid El Karkouri, Marion Chery, Divya Choudhary, Nicolas Vidal, Maria G Winter, Natasha W Tanner and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Maxence S VincentAix-Marseille Université, CNRS UMR 7283, Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, Marseille, France.ORCID 0000-0001-8431-7504
Laurent LoiseauAix-Marseille Université, CNRS UMR 7283, Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, Marseille, France.
Matthew JonesAix-Marseille Université, CNRS UMR 7283, Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, Marseille, France.
Pierre StockerAix-Marseille Université, CNRS UMR 7273, Institut de Chimie Radicalaire, Marseille, France.
Khalid El KarkouriAix-Marseille Université, CNRS UMR 7283, Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, Marseille, France.
Marion CheryAix-Marseille Université, CNRS UMR 7283, Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, Marseille, France.
Divya ChoudharyDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA, USA.
Nicolas VidalAix-Marseille Université, CNRS UMR 7273, Institut de Chimie Radicalaire, Marseille, France.
Maria G WinterDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis, Davis, CA, USA.
Natasha W TannerDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis, Davis, CA, USA.
Sylvia PietriAix-Marseille Université, CNRS UMR 7273, Institut de Chimie Radicalaire, Marseille, France.
Sebastian E WinterDepartment of Internal Medicine, Division of Infectious Diseases, UC Davis, Davis, CA, USA.ORCID 0000-0003-1532-9178
Benjamin EzratyAix-Marseille Université, CNRS UMR 7283, Laboratoire de Chimie Bactérienne, Institut de Microbiologie de la Méditerranée, Marseille, France.ORCID 0000-0003-3818-6907

Funding

Central metabolism of Salmonella in the inflamed gutR01AI118807 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI Sebastian E Winter · 2015 to 2026
$5.3M
Metabolic Interactions between Salmonella and E. coli Nissle 1917R21AI171537 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WINTER, SEBASTIAN E · 2022 to 2023
$439k
Mechanisms of Yersinia Enterocolitica Interaction with the Gut MicrobiotaR21AI188307 · NIAID · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Sebastian E Winter · 2025 to 2026
$437k
NIAID NIH HHS R01 AI118807NIAID NIH HHS R21 AI171537NIAID NIH HHS R21 AI188307
6 · The paper itself

Abstract

Uric acid, the final product of purine metabolism in humans, accumulates in blood and tissues at relatively high concentrations

Identifiers

PMID42282750
PMCPMC13252058

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.